HitPredict

Interactor 1: NPM (P06748)
Nucleophosmin (NPM) (Nucleolar phosphoprotein B23) (Nucleolar protein NO38) (Numatrin)
Gene: NPM1

Interactor 2: WDR75 (Q8IWA0)
WD repeat-containing protein 75 (U3 small nucleolar RNA-associated protein 17 homolog)
Gene: WDR75

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	39501047
Identification Methods	cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005654 - nucleoplasm GO:0005730 - nucleolus GO:0042274 - ribosomal small subunit biogenesis
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 294 Hs			1 830
+	Hs
		446952 NPM_HUMAN (1-294): 1.76e-143: 406: 100.00		TBL3_HUMAN (1-491): 1.58e-71: 252: 11.49
+	Hs
		447586 NPM_HUMAN (1-294): 1.76e-143: 406: 100.00		WDR3_HUMAN (510-738): 3.7e-19: 95: 15.95
+	Hs
		447501 NPM_HUMAN (1-294): 1.76e-143: 406: 100.00		NLE1_HUMAN (530-700): 1.6e-18: 91.5: 8.94
+	Hs
		446838 NPM_HUMAN (1-294): 1.76e-143: 406: 100.00		WDR5_HUMAN (528-697): 5.41e-19: 91.2: 11.79
+	Hs
		288642 NPM3_HUMAN (10-119): 6.16e-58: 185: 43.75		TBL3_HUMAN (1-491): 1.58e-71: 252: 11.49
+	Hs
		288819 NPM3_HUMAN (10-119): 6.16e-58: 185: 43.75		WDR3_HUMAN (510-738): 3.7e-19: 95: 15.95
+	Hs
		288793 NPM3_HUMAN (10-119): 6.16e-58: 185: 43.75		NLE1_HUMAN (530-700): 1.6e-18: 91.5: 8.94