HitPredict

Interactor 1: NPM (P06748)
Nucleophosmin (NPM) (Nucleolar phosphoprotein B23) (Nucleolar protein NO38) (Numatrin)
Gene: NPM1

Interactor 2: WDR36 (Q8NI36)
WD repeat-containing protein 36 (T-cell activation WD repeat-containing protein) (TA-WDRP)
Gene: WDR36

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	33961781, 39501047
Identification Methods	affinity chromatography technology, cross-linking study, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005654 - nucleoplasm GO:0042274 - ribosomal small subunit biogenesis
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 294 Hs			1 895
+	Hs
		288711 NPM3_HUMAN (10-119): 6.16e-58: 185: 43.75		WDR36_HUMAN (1-895): 0: 584: 100.00
+	Hs
		447501 NPM_HUMAN (1-294): 1.76e-143: 406: 100.00		NLE1_HUMAN (522-744): 3.85e-30: 127: 14.35
+	Hs
		447586 NPM_HUMAN (1-294): 1.76e-143: 406: 100.00		WDR3_HUMAN (536-770): 7.3e-25: 113: 16.21
+	Hs
		446838 NPM_HUMAN (1-294): 1.76e-143: 406: 100.00		WDR5_HUMAN (558-691): 1.89e-21: 98.6: 19.26
+	Hs
		447577 NPM_HUMAN (1-294): 1.76e-143: 406: 100.00		PRP19_HUMAN (472-647): 1.38e-20: 98.3: 16.37
+	Hs
		446952 NPM_HUMAN (1-294): 1.76e-143: 406: 100.00		TBL3_HUMAN (2-93): 1.46e-10: 67.2: 9.28
+	Hs
		288793 NPM3_HUMAN (10-119): 6.16e-58: 185: 43.75		NLE1_HUMAN (522-744): 3.85e-30: 127: 14.35
+	Hs
		288819 NPM3_HUMAN (10-119): 6.16e-58: 185: 43.75		WDR3_HUMAN (536-770): 7.3e-25: 113: 16.21
+	Hs
		288642 NPM3_HUMAN (10-119): 6.16e-58: 185: 43.75		TBL3_HUMAN (2-93): 1.46e-10: 67.2: 9.28