HitPredict

Interactor 1: HXB5 (P09067)
Homeobox protein Hox-B5 (Homeobox protein HHO.C10) (Homeobox protein Hox-2A) (Homeobox protein Hu-1)
Gene: HOXB5

Interactor 2: CTBP1 (Q13363)
C-terminal-binding protein 1 (CtBP1) (EC 1.1.1.-)
Gene: CTBP1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	25416956, 31515488
Identification Methods	two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006357 - regulation of transcription by RNA polymerase II
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 269 Hs			1 440
+	Hs
		447234 HXB5_HUMAN (1-269): 1.85e-52: 173: 100.00		CTBP2_HUMAN (10-439): 0: 538: 80.23
+	Hs
		595595 HXA5_HUMAN (1-269): 1.48e-44: 153: 55.72		CTBP2_HUMAN (10-439): 0: 538: 80.23
+	Hs
		881138 HXC5_HUMAN (1-261): 2.74e-32: 119: 40.23		CTBP2_HUMAN (10-439): 0: 538: 80.23
+	Dm
		220635 UBX_DROME (51-255): 5.65e-29: 114: 30.84		CTBP_DROME (1-361): 1.59e-142: 417: 70.91
+	Dm
		220629 ABDA_DROME (188-252): 8.22e-25: 105: 77.94		CTBP_DROME (1-361): 1.59e-142: 417: 70.91
+	Dm
		1367975 Q9W1H7_DROME (182-254): 2.15e-31: 117: 35.62		Q9VIJ0_DROME (2-349): 6.07e-113: 337: 22.88