HitPredict

Interactor 1: TPM3 (P06753)
Tropomyosin alpha-3 chain (Gamma-tropomyosin) (Tropomyosin-3) (Tropomyosin-5) (hTM5)
Gene: TPM3

Interactor 2: CDK9 (P50750)
Cyclin-dependent kinase 9 (EC 2.7.11.22) (EC 2.7.11.23) (C-2K) (Cell division cycle 2-like protein kinase 4) (Cell division protein kinase 9) (Serine/threonine-protein kinase PITALRE) (Tat-associated kinase complex catalytic subunit)
Gene: CDK9

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	26209609
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 285 Hs			1 372
+	Hs
		482860 TPM1_HUMAN (2-285): 1.36e-44: 154: 91.20		CDK9_HUMAN (1-372): 1.49e-148: 426: 100.00
+	Hs
		464132 TPM2_HUMAN (2-285): 1.41e-40: 143: 86.27		CDK9_HUMAN (1-372): 1.49e-148: 426: 100.00
+	Hs
		897727 TPM4_HUMAN (43-285): 3.76e-34: 126: 69.96		CDK9_HUMAN (1-372): 1.49e-148: 426: 100.00
+	Hs
		447677 TPM3_HUMAN (1-285): 1.29e-44: 154: 100.00		CDK2_HUMAN (16-321): 3.19e-137: 394: 38.76
+	Hs
		482834 TPM1_HUMAN (2-285): 1.36e-44: 154: 91.20		CDK2_HUMAN (16-321): 3.19e-137: 394: 38.76
+	Hs
		464114 TPM2_HUMAN (2-285): 1.41e-40: 143: 86.27		CDK2_HUMAN (16-321): 3.19e-137: 394: 38.76
+	Hs
		464115 TPM2_HUMAN (2-285): 1.41e-40: 143: 86.27		MK03_HUMAN (1-359): 4.07e-133: 387: 30.36
+	Hs
		116461 H7BYY1_HUMAN (41-285): 5.71e-36: 130: 64.90		CDK2_HUMAN (16-321): 3.19e-137: 394: 38.76
+	Hs
		667755 TPM4_HUMAN (43-285): 3.76e-34: 126: 69.96		CDK2_HUMAN (16-321): 3.19e-137: 394: 38.76