Interactor 1: CSF1R (P09581)
Macrophage colony-stimulating factor 1 receptor (CSF-1 receptor) (CSF-1-R) (CSF-1R) (M-CSF-R) (EC 2.7.10.1) (Proto-oncogene c-Fms) (CD antigen CD115)
Gene: CSF1R
Interactor 2: PLCG2 (Q8CIH5)
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 (EC 3.1.4.11) (Phosphoinositide phospholipase C-gamma-2) (Phospholipase C-gamma-2) (PLC-gamma-2)
Gene: PLCG2
Species: Mus musculus
Source: biogrid
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.46 | 1.00 | 0.680 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 9312046 |
| Identification Methods | pull down, two hybrid |
| Interaction Type | direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | PK_Tyr_Ser-Thr~SH2, PK_Tyr_Ser-Thr~SH3_1 |
| Common GO terms | GO:0005886 - plasma membrane GO:0010628 - positive regulation of gene expression GO:0032760 - positive regulation of tumor necrosis factor production GO:1902808 - positive regulation of cell cycle G1/S phase transition |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
