HitPredict

Interactor 1: PGFRB (P09619)
Platelet-derived growth factor receptor beta (PDGF-R-beta) (PDGFR-beta) (EC 2.7.10.1) (Beta platelet-derived growth factor receptor) (Beta-type platelet-derived growth factor receptor) (CD140 antigen-like family member B) (Platelet-derived growth factor receptor 1) (PDGFR-1) (CD antigen CD140b)
Gene: PDGFRB

Interactor 2: SNTB1 (Q13884)
Beta-1-syntrophin (59 kDa dystrophin-associated protein A1 basic component 1) (DAPA1B) (BSYN2) (Syntrophin-2) (Tax interaction protein 43) (TIP-43)
Gene: SNTB1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PH~PK_Tyr_Ser-Thr
Common GO terms	GO:0005737 - cytoplasm GO:0005925 - focal adhesion
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1106 Hs			1 538
+	Hs
		452413 PGFRB_HUMAN (1-1106): 0: 795: 100.00		SNTB2_HUMAN (19-537): 3.69e-141: 420: 54.41
+	Hs
		557115 PGFRA_HUMAN (3-1106): 0: 716: 42.48		SNTB2_HUMAN (19-537): 3.69e-141: 420: 54.41
+	Hs
		452485 PGFRB_HUMAN (1-1106): 0: 795: 100.00		GOPC_HUMAN (83-258): 5.81e-30: 124: 31.64
+	Ce
		1014310 EGL15_CAEEL (11-1064): 1.41e-153: 486: 16.68		SNT1_CAEEL (105-538): 1.29e-109: 335: 38.07
+	Hs
		507990 FGFR1_HUMAN (218-720): 1.52e-70: 254: 20.44		SNTB1_HUMAN (22-538): 6.02e-158: 462: 100.00
+	Hs
		507981 FGFR1_HUMAN (218-720): 1.52e-70: 254: 20.44		SNTB2_HUMAN (19-537): 3.69e-141: 420: 54.41
+	Hs
		609282 FGFR3_HUMAN (1-313): 7.09e-52: 198: 10.66		SNTB1_HUMAN (22-538): 6.02e-158: 462: 100.00
+	Hs
		729276 VGFR3_HUMAN (32-529): 2.63e-47: 187: 19.38		SNTB1_HUMAN (22-538): 6.02e-158: 462: 100.00
+	Hs
		609274 FGFR3_HUMAN (1-313): 7.09e-52: 198: 10.66		SNTB2_HUMAN (19-537): 3.69e-141: 420: 54.41
+	Hs
		1081612 NTRK3_HUMAN (65-966): 1.49e-133: 427: 16.58		GOPC_HUMAN (83-258): 5.81e-30: 124: 31.64
+	Hs
		1081620 NTRK3_HUMAN (65-966): 1.49e-133: 427: 16.58		LIN7C_HUMAN (108-197): 6.75e-30: 117: 42.22
+	Hs
		607963 FGFR4_HUMAN (200-413): 5.32e-14: 78.7: 17.73		SNTB1_HUMAN (22-538): 6.02e-158: 462: 100.00
+	Hs
		1021503 NTRK3_HUMAN (65-966): 1.49e-133: 427: 16.58		DLG1_HUMAN (77-203): 1.17e-21: 101: 33.33
+	Hs
		159144 FGFR1_HUMAN (218-720): 1.52e-70: 254: 20.44		CSKP_HUMAN (28-512): 1.27e-73: 253: 10.90
+	Hs
		607960 FGFR4_HUMAN (200-413): 5.32e-14: 78.7: 17.73		SNTB2_HUMAN (19-537): 3.69e-141: 420: 54.41
+	Hs
		508210 FGFR1_HUMAN (218-720): 1.52e-70: 254: 20.44		GOPC_HUMAN (83-258): 5.81e-30: 124: 31.64
+	Hs
		601598 FGFR2_HUMAN (9-326): 2.34e-58: 218: 11.51		GOPC_HUMAN (83-258): 5.81e-30: 124: 31.64
+	Hs
		609552 FGFR3_HUMAN (1-313): 7.09e-52: 198: 10.66		GOPC_HUMAN (83-258): 5.81e-30: 124: 31.64
+	Hs
		608144 FGFR4_HUMAN (200-413): 5.32e-14: 78.7: 17.73		GOPC_HUMAN (83-258): 5.81e-30: 124: 31.64
+	Hs
		608206 FGFR4_HUMAN (200-413): 5.32e-14: 78.7: 17.73		GRIP1_HUMAN (50-225): 3.95e-11: 67.9: 21.31