Protein: HDA10
Polyamine deacetylase HDAC10 (EC 3.5.1.48) (EC 3.5.1.62) (Histone deacetylase 10) (HD10)

Gene: HDA10, HDAC10
Organism: Homo sapiens
Interactions: 47
UniProt ID: Q969S8

Gene Ontology (top 5):
GO:0000118 - histone deacetylase complex
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0004407 - histone deacetylase activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1381099

NCOR2
Nuclear receptor corepressor 2

2

20

Small-scale

0.776

High

1100198

TIF1B
Transcription intermediary factor 1-beta

1

20

Small-scale

0.724

High

188335

HDAC3
Histone deacetylase 3

1

18

Small-scale

0.665

High

1368036

HDAC2
Histone deacetylase 2

1

18

Small-scale

0.665

High

932111

EPHA4
Ephrin type-A receptor 4

2

2

High-throughput

0.628

High

944842

PCBP3
Poly(rC)-binding protein 3

2

12

High-throughput

0.628

High

1241154

LTMD1
LETM1 domain-containing protein 1

2

1

High-throughput

0.628

High

1349720

P4K2B
Phosphatidylinositol 4-kinase type 2-beta

2

1

High-throughput

0.628

High

223640

NDUB5
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial

2

0

High-throughput

0.602

High

327398

ZFPL1
Zinc finger protein-like 1

2

0

High-throughput

0.602

High

1381093

ABHEA
Protein ABHD14A

2

0

High-throughput

0.602

High

1381094

TRI54
Tripartite motif-containing protein 54

1

12

High-throughput

0.568

High

537657

HSP7C
Heat shock cognate 71 kDa protein

1

12

Small-scale

0.561

High

662323

PAX3
Paired box protein Pax-3

1

2

Small-scale

0.561

High

183173

GNPAT
Dihydroxyacetone phosphate acyltransferase

1

2

High-throughput

0.536

High

581216

RAC2
Ras-related C3 botulinum toxin substrate 2

1

7

High-throughput

0.536

High

717566

PDIA3
Protein disulfide-isomerase A3

1

8

High-throughput

0.536

High

727913

DNJA1
DnaJ homolog subfamily A member 1

1

11

High-throughput

0.536

High

921741

COPB
Coatomer subunit beta

1

8

High-throughput

0.536

High

1191923

TBB8
Tubulin beta-8 chain

1

16

High-throughput

0.536

High

1381097

SPG7
Mitochondrial inner membrane m-AAA protease component paraplegin

1

6

High-throughput

0.536

High

843838

HD
Huntingtin

1

2

High-throughput

0.515

High

927090

ATX3
Ataxin-3

1

3

High-throughput

0.515

High

1369604

APBB2
Amyloid beta precursor protein binding family B member 2

1

1

High-throughput

0.515

High

1381092

OPTN
Optineurin

1

20

High-throughput

0.515

High

567048

P4HA1
Prolyl 4-hydroxylase subunit alpha-1

1

0

High-throughput

0.513

High

791609

SYUA
Alpha-synuclein

1

0

High-throughput

0.493

High

1277817

PEX26
Peroxisome assembly protein 26

1

0

High-throughput

0.493

High

847428

GPDM
Glycerol-3-phosphate dehydrogenase, mitochondrial

1

1

High-throughput

0.489

High

1334111

TXND5
Thioredoxin domain-containing protein 5

1

10

High-throughput

0.489

High

180163

ZBT7B
Zinc finger and BTB domain-containing protein 7B

1

20

Small-scale

0.479

High

228337

CPSF5
Cleavage and polyadenylation specificity factor subunit 5

1

2

Small-scale

0.479

High

617180

ATF3
Cyclic AMP-dependent transcription factor ATF-3

1

20

Small-scale

0.479

High

888234

MCM2
DNA replication licensing factor MCM2

1

14

High-throughput

0.479

High

899762

PAPOA
Poly(A) polymerase alpha

1

1

Small-scale

0.479

High

1138481

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

8

High-throughput

0.479

High

1361623

JDP2
Jun dimerization protein 2

1

20

Small-scale

0.479

High

1381095

MYO10
Unconventional myosin-X

1

16

Small-scale

0.479

High

1381096

PIHD1
PIH1 domain-containing protein 1

1

1

High-throughput

0.479

High

869775

MTR1A
Melatonin receptor type 1A

1

1

High-throughput

0.464

High

786765

PP1G
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

1

12

Small-scale

0.445

High

184890

SPTC1
Serine palmitoyltransferase 1

1

2

High-throughput

0.437

High

1381098

AAR2
Protein AAR2 homolog

1

1

High-throughput

0.437

High

1129682

MDC1
Mediator of DNA damage checkpoint protein 1

1

9

Small-scale

0.408

High

462794

QCR6
Cytochrome b-c1 complex subunit 6, mitochondrial

2

0

High-throughput

0.328

High

789944

FDFT
Squalene synthase

1

0

High-throughput

0.279

Low

47388

A0A6Q8PF08
Peripheral myelin protein 22

1

0

High-throughput

0.268

Low


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Last updated: 11Aug2025