HitPredict

Interactor 1: CTNB1 (P35222)
Catenin beta-1 (Beta-catenin)
Gene: CTNNB1

Interactor 2: FBXW2 (Q9UKT8)
F-box/WD repeat-containing protein 2 (F-box and WD-40 domain-containing protein 2) (Protein MD6)
Gene: FBXW2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.64	0.60	0.624

Property	Details
Experiments	30918250, 37820851
Identification Methods	affinity chromatography technology, enzymatic study
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 781 Hs			1 454
+	Hs
		717449 CTNB1_HUMAN (1-781): 0: 626: 100.00		FBW1A_HUMAN (23-313): 2.4e-60: 208: 17.97
+	Mm
		970129 CTNB1_MOUSE (1-781): 0: 624: 99.87		FBW1A_MOUSE (23-309): 1.26e-59: 206: 17.88
+	Hs
		717264 CTNB1_HUMAN (1-781): 0: 626: 100.00		FBXW7_HUMAN (32-264): 4.84e-57: 201: 21.85
+	Xl
		1193353 Q7ZX35_XENLA (1-781): 0: 622: 97.31		TRCB_XENLA (23-309): 5.06e-59: 203: 18.54
+	Hs
		245567 CTNB1_HUMAN (1-781): 0: 626: 100.00		TBL1X_HUMAN (30-257): 4.63e-44: 164: 16.05
+	Hs
		717329 CTNB1_HUMAN (1-781): 0: 626: 100.00		TBL1R_HUMAN (7-177): 8.92e-19: 90.6: 8.15
+	Hs
		717413 CTNB1_HUMAN (1-781): 0: 626: 100.00		FBW1B_HUMAN (31-188): 8.64e-19: 90.6: 13.64
+	Hs
		716939 CTNB1_HUMAN (1-781): 0: 626: 100.00		WDR5_HUMAN (353-451): 3.15e-13: 72.5: 6.93
+	Hs
		542482 PLAK_HUMAN (8-752): 2.69e-158: 479: 67.42		FBW1A_HUMAN (23-313): 2.4e-60: 208: 17.97
+	Hs
		542400 PLAK_HUMAN (8-752): 2.69e-158: 479: 67.42		FBXW7_HUMAN (32-264): 4.84e-57: 201: 21.85
+	Dm
		578711 ARM_DROME (1-780): 9.15e-160: 486: 64.49		Q9VDE3_DROME (12-260): 2.83e-42: 158: 17.94
+	Ce
		1000138 BAR1_CAEEL (129-740): 4.72e-102: 334: 24.15		LIN23_CAEEL (5-450): 2.64e-89: 287: 19.04
+	Hs
		542260 PLAK_HUMAN (8-752): 2.69e-158: 479: 67.42		WDR5_HUMAN (353-451): 3.15e-13: 72.5: 6.93
+	Hs
		131484 IMA4_HUMAN (220-681): 6.79e-68: 235: 15.25		FBXW7_HUMAN (32-264): 4.84e-57: 201: 21.85
+	Hs
		209410 IMA1_HUMAN (237-675): 3.54e-66: 231: 18.54		PLRG1_HUMAN (96-390): 6.55e-51: 181: 19.94
+	Hs
		209411 IMA5_HUMAN (240-678): 2.52e-65: 228: 16.44		PLRG1_HUMAN (96-390): 6.55e-51: 181: 19.94
+	Hs
		853512 IMA1_HUMAN (237-675): 3.54e-66: 231: 18.54		FBW1B_HUMAN (31-188): 8.64e-19: 90.6: 13.64
+	Sc
		744674 IMA1_YEAST (219-692): 2.13e-70: 242: 15.26		TAF5_YEAST (163-259): 1.2e-14: 78.2: 39.22
+	Hs
		238721 IMA7_HUMAN (200-683): 8.41e-73: 249: 16.97		SNR40_HUMAN (129-253): 8.52e-12: 68.2: 31.25
+	Hs
		131487 IMA4_HUMAN (220-681): 6.79e-68: 235: 15.25		SNR40_HUMAN (129-253): 8.52e-12: 68.2: 31.25