HitPredict

Interactor 1: ROA1 (P09651)
Heterogeneous nuclear ribonucleoprotein A1 (hnRNP A1) (Helix-destabilizing protein) (Single-strand RNA-binding protein) (hnRNP core protein A1) [Cleaved into: Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed]
Gene: HNRNPA1

Interactor 2: SRSF9 (Q13242)
Serine/arginine-rich splicing factor 9 (Pre-mRNA-splicing factor SRp30C) (Splicing factor, arginine/serine-rich 9)
Gene: SRSF9

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	34079125, 37071682
Identification Methods	proximity labelling technology, cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0003723 - RNA binding GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0019904 - protein domain specific binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 372 Hs			1 221
+	Hs
		453308 ROA1_HUMAN (1-372): 3.69e-61: 202: 100.00		SRSF1_HUMAN (1-183): 1.13e-57: 184: 69.95
+	Hs
		453328 ROA1_HUMAN (1-372): 3.69e-61: 202: 100.00		SRSF6_HUMAN (15-176): 1.67e-51: 171: 36.67
+	Hs
		453309 ROA1_HUMAN (1-372): 3.69e-61: 202: 100.00		SRSF4_HUMAN (15-169): 2.97e-47: 164: 39.52
+	Mm
		825794 ROA1_MOUSE (1-302): 7.42e-58: 192: 86.09		SRSF9_MOUSE (2-221): 5.95e-54: 173: 98.64
+	Hs
		453107 ROA1_HUMAN (1-372): 3.69e-61: 202: 100.00		PABP1_HUMAN (12-193): 1.8e-42: 153: 20.00
+	Hs
		161948 HNRDL_HUMAN (2-283): 5.5e-56: 190: 32.41		PABP1_HUMAN (12-193): 1.8e-42: 153: 20.00
+	Hs
		516358 ROA2_HUMAN (1-339): 4.42e-56: 188: 59.00		PABP1_HUMAN (12-193): 1.8e-42: 153: 20.00
+	Hs
		516424 ROA3_HUMAN (7-202): 5.98e-55: 186: 85.71		PABP1_HUMAN (12-193): 1.8e-42: 153: 20.00
+	Hs
		453331 ROA1_HUMAN (1-372): 3.69e-61: 202: 100.00		PABP4_HUMAN (5-104): 2.37e-21: 93.4: 19.80
+	Hs
		516689 PABP3_HUMAN (6-193): 6.86e-35: 137: 17.90		PABP1_HUMAN (12-193): 1.8e-42: 153: 20.00
+	Hs
		516663 ROAA_HUMAN (6-184): 1.25e-35: 134: 39.44		PABP1_HUMAN (12-193): 1.8e-42: 153: 20.00
+	Sc
		376899 PABP_YEAST (4-189): 6.12e-39: 147: 24.47		NOP3_YEAST (7-179): 6.54e-38: 137: 27.68
+	Hs
		992743 ELAV2_HUMAN (1-186): 1.4e-22: 99.5: 14.98		SRSF1_HUMAN (1-183): 1.13e-57: 184: 69.95
+	Hs
		162035 HNRDL_HUMAN (2-283): 5.5e-56: 190: 32.41		PABP4_HUMAN (5-104): 2.37e-21: 93.4: 19.80
+	Hs
		201707 MSI1H_HUMAN (2-340): 5.33e-59: 196: 27.87		RBM4B_HUMAN (5-102): 8.16e-18: 82.6: 20.41
+	Hs
		1020247 ELAV2_HUMAN (1-186): 1.4e-22: 99.5: 14.98		SRSF6_HUMAN (15-176): 1.67e-51: 171: 36.67
+	Hs
		516484 ELAV2_HUMAN (1-186): 1.4e-22: 99.5: 14.98		PABP1_HUMAN (12-193): 1.8e-42: 153: 20.00
+	Sc
		376562 PABP_YEAST (4-189): 6.12e-39: 147: 24.47		PABP_YEAST (113-192): 2.4e-13: 70.3: 20.69
+	Hs
		1020249 ELAV2_HUMAN (1-186): 1.4e-22: 99.5: 14.98		PABP4_HUMAN (5-104): 2.37e-21: 93.4: 19.80
+	Hs
		474019 ELAV2_HUMAN (1-186): 1.4e-22: 99.5: 14.98		PAB4L_HUMAN (108-183): 6.59e-12: 65.7: 14.46