HitPredict

Interactor 1: ROA1 (P09651)
Heterogeneous nuclear ribonucleoprotein A1 (hnRNP A1) (Helix-destabilizing protein) (Single-strand RNA-binding protein) (hnRNP core protein A1) [Cleaved into: Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed]
Gene: HNRNPA1

Interactor 2: DDX28 (Q9NUL7)
Probable ATP-dependent RNA helicase DDX28 (EC 3.6.4.13) (Mitochondrial DEAD box protein 28)
Gene: DDX28

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	25324306, 22446626
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 372 Hs			1 540
+	Hs
		453579 ROA1_HUMAN (1-372): 3.69e-61: 202: 100.00		DDX23_HUMAN (80-540): 8.1e-154: 461: 27.20
+	Hs
		453509 ROA1_HUMAN (1-372): 3.69e-61: 202: 100.00		DDX17_HUMAN (59-535): 4.77e-132: 403: 24.90
+	Hs
		453133 ROA1_HUMAN (1-372): 3.69e-61: 202: 100.00		DDX5_HUMAN (51-535): 8.85e-133: 401: 26.34
+	Hs
		162171 HNRDL_HUMAN (2-283): 5.5e-56: 190: 32.41		DDX28_HUMAN (1-540): 2.48e-135: 405: 100.00
+	Hs
		161959 HNRDL_HUMAN (2-283): 5.5e-56: 190: 32.41		DDX5_HUMAN (51-535): 8.85e-133: 401: 26.34
+	Hs
		571307 ROA2_HUMAN (1-339): 4.42e-56: 188: 59.00		DDX5_HUMAN (51-535): 8.85e-133: 401: 26.34
+	Hs
		133852 ROA1_HUMAN (1-372): 3.69e-61: 202: 100.00		DDX3X_HUMAN (4-536): 2.55e-126: 386: 20.84
+	Hs
		571368 ROA3_HUMAN (7-202): 5.98e-55: 186: 85.71		DDX5_HUMAN (51-535): 8.85e-133: 401: 26.34
+	Sc
		376580 PABP_YEAST (4-189): 6.12e-39: 147: 24.47		DED1_YEAST (105-537): 3.67e-144: 429: 24.04
+	Dm
		973550 RB97D_DROME (9-181): 5.67e-47: 167: 49.13		Q9W3M7_DROME (15-539): 1.02e-127: 397: 24.20
+	Hs
		1048159 HNRPD_HUMAN (2-101): 4.8e-18: 86.4: 31.00		DDX17_HUMAN (59-535): 4.77e-132: 403: 24.90
+	Hs
		134018 PABP4_HUMAN (102-190): 3.52e-15: 79: 15.56		DDX3X_HUMAN (4-536): 2.55e-126: 386: 20.84
+	Mm
		857351 TIA1_MOUSE (99-193): 5.17e-09: 59.4: 17.71		Q8BTS0_MOUSE (51-535): 9.94e-133: 401: 26.34
+	Mm
		857323 TIA1_MOUSE (99-193): 5.17e-09: 59.4: 17.71		DDX17_MOUSE (59-535): 2.99e-132: 400: 24.90
+	Hs
		453740 ROA1_HUMAN (1-372): 3.69e-61: 202: 100.00		DDX49_HUMAN (128-522): 1.24e-39: 152: 31.92