HitPredict

Interactor 1: PARP1 (P09874)
Poly [ADP-ribose] polymerase 1 (PARP-1) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 1) (ARTD1) (DNA ADP-ribosyltransferase PARP1) (EC 2.4.2.-) (NAD(+) ADP-ribosyltransferase 1) (ADPRT 1) (Poly[ADP-ribose] synthase 1) (Protein poly-ADP-ribosyltransferase PARP1) (EC 2.4.2.-) [Cleaved into: Poly [ADP-ribose] polymerase 1, processed C-terminus (Poly [ADP-ribose] polymerase 1, 89-kDa form); Poly [ADP-ribose] polymerase 1, processed N-terminus (NT-PARP-1) (Poly [ADP-ribose] polymerase 1, 24-kDa form) (Poly [ADP-ribose] polymerase 1, 28-kDa form)]
Gene: PARP1

Interactor 2: NCBP2 (P52298)
Nuclear cap-binding protein subunit 2 (20 kDa nuclear cap-binding protein) (Cell proliferation-inducing gene 55 protein) (NCBP 20 kDa subunit) (CBP20) (NCBP-interacting protein 1) (NIP1)
Gene: NCBP2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	32960270
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 1014 Hs			1 156
+	Hs
		853932 PARPT_HUMAN (710-1006): 4.56e-65: 234: 15.84		NCBP2_HUMAN (1-156): 2.27e-48: 154: 100.00
+	Hs
		703399 PARPT_HUMAN (710-1006): 4.56e-65: 234: 15.84		CSTF2_HUMAN (31-148): 1.11e-34: 128: 23.53
+	Hs
		1031374 PARPT_HUMAN (710-1006): 4.56e-65: 234: 15.84		PABP4_HUMAN (4-156): 2.89e-27: 107: 17.18
+	Hs
		516572 ZCCHV_HUMAN (798-1005): 5.42e-21: 101: 15.71		PABP1_HUMAN (4-156): 7.45e-28: 109: 18.41
+	Hs
		1031373 ZCCHV_HUMAN (798-1005): 5.42e-21: 101: 15.71		PABP4_HUMAN (4-156): 2.89e-27: 107: 17.18