HitPredict

Interactor 1: PPBI (P09923)
Intestinal-type alkaline phosphatase (IAP) (Intestinal alkaline phosphatase) (EC 3.1.3.1)
Gene: ALPI

Interactor 2: NT2NA (Q7Z3S9)
Notch homolog 2 N-terminal-like protein A (Notch homolog 2 N-terminal-like protein)
Gene: NOTCH2NLA

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	25416956, 31515488
Identification Methods	two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005576 - extracellular region
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 528 Hs			1 236
+	Hs
		398549 PPB1_HUMAN (20-513): 0: 797: 87.05		NT2NA_HUMAN (1-236): 1e-44: 151: 100.00
+	Hs
		398593 PPB1_HUMAN (20-513): 0: 797: 87.05		JAG2_HUMAN (8-209): 1.76e-16: 80.1: 31.86
+	Hs
		398485 PPB1_HUMAN (20-513): 0: 797: 87.05		NT2NC_HUMAN (69-233): 8.71e-14: 70.8: 32.95
+	Dm
		706657 Q9VP35_DROME (23-499): 0: 629: 44.72		FAT_DROME (145-236): 1.12e-20: 92.4: 24.17