HitPredict

Interactor 1: RIR2 (P09938)
Ribonucleoside-diphosphate reductase small chain 1 (EC 1.17.4.1) (Ribonucleotide reductase R2 subunit 1) (Ribonucleotide reductase small subunit 1)
Gene: RNR2

Interactor 2: RIR4 (P49723)
Ribonucleoside-diphosphate reductase small chain 2 (EC 1.17.4.1) (Ribonucleotide reductase R2 subunit 2) (Ribonucleotide reductase small subunit 2)
Gene: RNR4

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 1.00 0.984

The method score is based on:

Property Details
Experiments 10535923, 21336276, 10716984, 9315670, 16432237, 16554755, 16429126, 16489218, 11526232, 37968396, 20826334, 23532842, 11526233
Identification Methods biochemical, pull down, cosedimentation through density gradient, coimmunoprecipitation, affinity chromatography technology, anti tag coimmunoprecipitation, x-ray crystallography, circular dichroism, tandem affinity purification
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Ribonuc_red_sm~Ribonuc_red_sm
Common GO terms GO:0004748 - ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005971 - ribonucleoside-diphosphate reductase complex
GO:0009263 - deoxyribonucleotide biosynthetic process
and 1 others

more...
Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 399
Sc

1 345
+ Sc
+ Hs
+ Hs
+ Hs
+ Vv
+ Ce
+ Sc
+ Hh
+ Hh
+ Hh
+ Ha
+ Ec
+ Ec
+ Mp
+ Mt

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024