HitPredict

Interactor 1: UBC (P0CG48)
Polyubiquitin-C [Cleaved into: Ubiquitin]
Gene: UBC

Interactor 2: STAM1 (Q92783)
Signal transducing adapter molecule 1 (STAM-1)
Gene: STAM

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.96	1.00	0.982

Property	Details
Experiments	20504764, 26456826, 23035694, 28190767, 31699778, 38803224, 23314748, 21187078, 26601948, 17078930, 16771824, 19111546, 12750381, 20150893
Identification Methods	pull down, x-ray crystallography, unspecified method, affinity chromatography technology, nuclear magnetic resonance, surface plasmon resonance
Interaction Type	direct interaction, association, physical association

Property	Details
Interacting Pfam domains	SH3_1~ubiquitin, UIM~ubiquitin, VHS~ubiquitin
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 685 Hs			1 540
+	Hs
		276993 UBC_HUMAN (1-685): 0: 846: 100.00		STAM2_HUMAN (1-533): 8.53e-122: 369: 54.65
+	Hs
		475949 UBC_HUMAN (1-685): 0: 846: 100.00		TM1L2_HUMAN (6-435): 1.81e-70: 236: 18.45
+	Hs
		241137 UBC_HUMAN (1-685): 0: 846: 100.00		TOM1_HUMAN (6-454): 3.66e-69: 232: 16.81
+	Hs
		476481 UBC_HUMAN (1-685): 0: 846: 100.00		GGA3_HUMAN (1-530): 3.3e-63: 221: 15.64
+	Hs
		476541 UBC_HUMAN (1-685): 0: 846: 100.00		GGA1_HUMAN (2-526): 3.1e-56: 201: 14.00
+	Hs
		272789 UBC_HUMAN (1-685): 0: 846: 100.00		TM1L1_HUMAN (6-504): 8.91e-52: 185: 16.27
+	Bt
		477668 UBC_BOVIN (1-613): 0: 753: 99.18		Q58CQ6_BOVIN (2-394): 2.98e-56: 196: 15.06
+	Hs
		159860 UBC_HUMAN (1-685): 0: 846: 100.00		HGS_HUMAN (84-540): 8.62e-15: 79.4: 13.50
+	Hs
		475592 UBC_HUMAN (1-685): 0: 846: 100.00		GRB2_HUMAN (215-265): 2.32e-13: 71.2: 54.90
+	Dm
		477530 UBIQP_DROME (1-610): 0: 752: 99.84		HRS_DROME (7-145): 4.23e-40: 156: 31.43
+	Sc
		477263 UBI4P_YEAST (381-685): 5e-122: 370: 95.74		HSE1_YEAST (15-488): 6.22e-57: 198: 21.37
+	Sc
		477270 UBI4P_YEAST (381-685): 5e-122: 370: 95.74		GGA2_YEAST (2-438): 4.97e-48: 177: 16.67
+	Sc
		477454 UBI4P_YEAST (381-685): 5e-122: 370: 95.74		GGA1_YEAST (2-421): 6.35e-48: 176: 16.40
+	Hs
		277047 RS27A_HUMAN (609-684): 7.23e-41: 148: 100.00		STAM2_HUMAN (1-533): 8.53e-122: 369: 54.65
+	Sc
		477314 UBI4P_YEAST (381-685): 5e-122: 370: 95.74		VPS27_YEAST (1-163): 3.77e-36: 144: 26.63
+	Ce
		136432 UBIQ1_CAEEL (1-229): 5.97e-87: 292: 98.25		STAM1_CAEEL (4-409): 5.04e-65: 220: 29.61
+	Ce
		477552 UBIQ1_CAEEL (1-229): 5.97e-87: 292: 98.25		Q17796_CAEEL (6-388): 3.6e-59: 210: 16.62
+	At
		1092009 UBQ3_ARATH (457-685): 3.23e-85: 272: 95.63		TOL5_ARATH (9-240): 1.05e-40: 154: 17.57
+	At
		285943 UBQ3_ARATH (457-685): 3.23e-85: 272: 95.63		TOL6_ARATH (14-161): 1.75e-31: 131: 26.00
+	Hs
		923946 RS27A_HUMAN (609-684): 7.23e-41: 148: 100.00		GRB2_HUMAN (215-265): 2.32e-13: 71.2: 54.90