Protein: FBN1
Fibrillin-1 [Cleaved into: Asprosin]

Gene: FBN1
Organism: Homo sapiens
Interactions: 52
UniProt ID: P35555

Gene Ontology (top 5):
GO:0001501 - skeletal system development
GO:0001527 - microfibril
GO:0001656 - metanephros development
GO:0005178 - integrin binding
GO:0005179 - hormone activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

772271

FBN1
Fibrillin-1 [Cleaved into: Asprosin]

3

18

Small-scale

0.857

High

389094

FINC
Fibronectin

2

9

Small-scale

0.768

High

772272

FBN2
Fibrillin-2 [Cleaved into: Placensin]

2

19

Small-scale

0.768

High

351510

FBLN4
EGF-containing fibulin-like extracellular matrix protein 2

1

17

Small-scale

0.724

High

772282

LTBP1
Latent-transforming growth factor beta-binding protein 1

1

18

Small-scale

0.724

High

772301

ST14
Suppressor of tumorigenicity 14 protein

1

11

High-throughput

0.691

High

772274

MFAP2
Microfibrillar-associated protein 2

3

5

Small-scale

0.651

High

565088

CSPG2
Versican core protein

1

18

Small-scale

0.647

High

772278

FBLN2
Fibulin-2

1

18

Small-scale

0.647

High

772288

LTBP4
Latent-transforming growth factor beta-binding protein 4

1

18

Small-scale

0.647

High

772299

FBLN5
Fibulin-5

1

18

Small-scale

0.647

High

772285

ODAPH
Odontogenesis associated phosphoprotein

2

2

High-throughput

0.628

High

702174

LYOX
Protein-lysine 6-oxidase

2

6

Small-scale

0.624

High

464422

TSP1
Thrombospondin-1

1

18

Small-scale

0.618

High

584617

ELN
Elastin

2

7

Small-scale

0.611

High

772289

ZFP41
Zinc finger protein 41 homolog

3

20

High-throughput

0.609

High

772300

FBX2
F-box only protein 2

3

20

Small-scale

0.593

High

772298

ZN408
Zinc finger protein 408

2

20

High-throughput

0.574

High

323969

CSTN1
Calsyntenin-1

1

16

Small-scale

0.561

High

169462

HGS
Hepatocyte growth factor-regulated tyrosine kinase substrate

2

3

High-throughput

0.553

High

772293

SGTB
Small glutamine-rich tetratricopeptide repeat-containing protein beta

2

5

High-throughput

0.553

High

772273

HXA1
Homeobox protein Hox-A1

1

11

High-throughput

0.541

High

405599

HRG
Histidine-rich glycoprotein

1

3

High-throughput

0.536

High

772291

NET5
Netrin-5

1

20

High-throughput

0.536

High

772296

MYOC
Myocilin

1

2

Small-scale

0.501

High

772275

MFAP4
Microfibril-associated glycoprotein 4

1

5

Small-scale

0.494

High

772281

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

6

High-throughput

0.494

High

772292

S39A7
Zinc transporter SLC39A7

1

5

High-throughput

0.489

High

217894

TGON2
Trans-Golgi network integral membrane protein 2

1

13

High-throughput

0.479

High

476102

ANXA5
Annexin A5

1

2

Small-scale

0.479

High

590822

TIMP2
Metalloproteinase inhibitor 2

1

6

High-throughput

0.479

High

609865

IBP3
Insulin-like growth factor-binding protein 3

1

15

Small-scale

0.479

High

665951

IBP5
Insulin-like growth factor-binding protein 5

1

15

Small-scale

0.479

High

705258

GRN
Progranulin

1

1

Small-scale

0.479

High

724539

S10A7
Protein S100-A7

1

1

Small-scale

0.479

High

772276

TGFB2
Transforming growth factor beta-2 proprotein

1

9

Small-scale

0.479

High

772279

LOXL1
Lysyl oxidase homolog 1

1

6

Small-scale

0.479

High

772280

CUL3
Cullin-3

1

16

High-throughput

0.479

High

772283

BGH3
Transforming growth factor-beta-induced protein ig-h3

1

1

Small-scale

0.479

High

772284

IBP7
Insulin-like growth factor-binding protein 7

1

8

Small-scale

0.479

High

772286

ATL5
ADAMTS-like protein 5

1

12

Small-scale

0.479

High

184689

ATX7
Ataxin-7

1

6

High-throughput

0.464

High

221091

SPY2
Protein sprouty homolog 2

1

3

High-throughput

0.464

High

464842

SP1
Transcription factor Sp1

1

20

High-throughput

0.457

High

323206

TRI37
E3 ubiquitin-protein ligase TRIM37

1

14

High-throughput

0.437

High

772290

NUP43
Nucleoporin Nup43

1

9

High-throughput

0.437

High

772294

ZDH15
Palmitoyltransferase ZDHHC15

1

2

Small-scale

0.437

High

772295

RANB9
Ran-binding protein 9

1

4

High-throughput

0.437

High

772297

WDR76
WD repeat-containing protein 76

1

7

High-throughput

0.437

High

772277

RHOB
Rho-related GTP-binding protein RhoB

1

20

Small-scale

0.417

High

772287

GET4
Golgi to ER traffic protein 4 homolog

2

0

High-throughput

0.316

High


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Last updated: 11Aug2025