HitPredict

Interactor 1: CAN1 (P07384)
Calpain-1 catalytic subunit (EC 3.4.22.52) (Calcium-activated neutral proteinase 1) (CANP 1) (Calpain mu-type) (Calpain-1 large subunit) (Cell proliferation-inducing gene 30 protein) (Micromolar-calpain) (muCANP)
Gene: CAPN1

Interactor 2: KCTD7 (Q96MP8)
BTB/POZ domain-containing protein KCTD7
Gene: KCTD7

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.52	1.00	0.724

Property	Details
Experiments	36964131
Identification Methods	affinity chromatography technology, enzymatic study
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	BTB_2~EF-hand_8
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 714 Hs			1 289
+	Hs
		606024 CAN2_HUMAN (13-708): 0: 907: 63.08		KCTD7_HUMAN (1-289): 7.18e-107: 313: 100.00
+	Mm
		147386 CAN2_MOUSE (13-708): 0: 906: 62.36		BACD1_MOUSE (13-180): 1.4e-43: 153: 32.95
+	Hs
		1236116 CAN13_HUMAN (32-713): 0: 607: 33.00		KCTD7_HUMAN (1-289): 7.18e-107: 313: 100.00
+	Hs
		191997 CAN5_HUMAN (37-525): 0: 563: 37.07		KCTD7_HUMAN (1-289): 7.18e-107: 313: 100.00
+	Hs
		1398296 CAN7_HUMAN (3-535): 1.98e-141: 435: 21.86		KCTD7_HUMAN (1-289): 7.18e-107: 313: 100.00
+	Hs
		294792 CAN15_HUMAN (42-504): 4.04e-129: 410: 28.01		KCTD7_HUMAN (1-289): 7.18e-107: 313: 100.00
+	Hs
		1117904 Q7Z479_HUMAN (3-535): 4.51e-141: 435: 21.86		BACD2_HUMAN (23-181): 3.77e-43: 151: 28.40
+	Hs
		1117936 CAN7_HUMAN (3-535): 1.98e-141: 435: 21.86		BACD2_HUMAN (23-181): 3.77e-43: 151: 28.40
+	Hs
		412975 CPNS1_HUMAN (510-714): 5.85e-56: 194: 43.13		KCTD7_HUMAN (1-289): 7.18e-107: 313: 100.00
+	Hs
		1398292 CAN10_HUMAN (362-534): 7.05e-13: 73.9: 25.43		KCTD7_HUMAN (1-289): 7.18e-107: 313: 100.00