HitPredict

Interactor 1: SEC4 (P07560)
Ras-related protein SEC4 (Suppressor of RHO3 protein 6)
Gene: SEC4

Interactor 2: PRA1 (P53633)
Prenylated Rab acceptor 1
Gene: YIP3

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.573

Property	Details
Experiments	11785952
Identification Methods	affinity chromatography technology, two hybrid, anti bait coimmunoprecipitation
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005783 - endoplasmic reticulum
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 215 Sc			1 176
+	At
		306628 RAE1C_ARATH (16-215): 1.31e-80: 241: 52.40		PR1B4_ARATH (8-174): 1.3e-61: 191: 17.16
+	At
		1441500 RABD1_ARATH (13-215): 5.82e-79: 236: 50.00		PR1F4_ARATH (1-175): 3.89e-63: 194: 21.71
+	At
		701376 RAE1C_ARATH (16-215): 1.31e-80: 241: 52.40		PR1F3_ARATH (1-175): 1.83e-59: 185: 18.86
+	At
		235784 RAA1E_ARATH (8-215): 3.64e-79: 237: 36.28		PR1F3_ARATH (1-175): 1.83e-59: 185: 18.86
+	Sc
		376327 YPT1_YEAST (13-215): 1.77e-84: 250: 47.09		PRA1_YEAST (1-176): 1.38e-50: 162: 100.00
+	At
		701377 RAE1C_ARATH (16-215): 1.31e-80: 241: 52.40		PR1B6_ARATH (27-176): 5.7e-52: 167: 21.71
+	Hs
		981377 RAB1A_HUMAN (10-215): 7.21e-85: 251: 49.28		PRAF1_HUMAN (26-174): 5.4e-47: 153: 26.67
+	At
		1443883 RABD1_ARATH (13-215): 5.82e-79: 236: 50.00		PR1B6_ARATH (27-176): 5.7e-52: 167: 21.71
+	At
		201161 RAE1A_ARATH (16-215): 2.46e-79: 238: 53.85		PR1B2_ARATH (3-174): 1.88e-51: 165: 20.69
+	At
		1456647 RABD1_ARATH (13-215): 5.82e-79: 236: 50.00		PR1B2_ARATH (3-174): 1.88e-51: 165: 20.69
+	Hs
		1430486 RAB1B_HUMAN (13-215): 2.51e-83: 247: 49.02		PRAF1_HUMAN (26-174): 5.4e-47: 153: 26.67
+	Rn
		204787 RAB1A_RAT (10-215): 7.21e-85: 251: 49.28		PRAF1_RAT (26-174): 1.66e-45: 149: 26.00