HitPredict

Interactor 1: IHFA (P0A6X7)
Integration host factor subunit alpha (IHF-alpha)
Gene: IHFA

Interactor 2: DBHB (P0ACF4)
DNA-binding protein HU-beta (HU-1) (NS1)
Gene: hupB

Species: Escherichia coli K-12

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.57	1.00	0.759

Property	Details
Experiments	19402753, 15690043
Identification Methods	tandem affinity purification, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Bac_DNA_binding~Bac_DNA_binding
Common GO terms	GO:0003677 - DNA binding GO:0005829 - cytosol GO:0006351 - DNA-templated transcription GO:0030527 - structural constituent of chromatin
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 99 Ec			1 90
+	Ec
		458964 IHFA_ECOLI (1-99): 2.27e-38: 125: 100.00		IHFB_ECOLI (1-90): 3.16e-34: 114: 35.17
+	Nv
		1175510 Q726Y3_NITV2 (3-91): 5.47e-36: 118: 32.58		Q72B43_NITV2 (1-89): 9.45e-30: 102: 53.93
+	Nv
		1175739 Q72AX6_NITV2 (3-89): 4.45e-35: 117: 31.03		Q72F19_NITV2 (1-90): 2.79e-29: 102: 27.78
+	Ec
		459009 IHFB_ECOLI (3-90): 1.25e-32: 110: 32.58		DBHB_ECOLI (1-90): 4.35e-32: 108: 100.00
+	Ec
		459008 IHFB_ECOLI (3-90): 1.25e-32: 110: 32.58		DBHA_ECOLI (1-89): 2.15e-30: 104: 69.66
+	Ec
		467149 DBHB_ECOLI (3-91): 1.7e-30: 105: 32.58		DBHB_ECOLI (1-90): 4.35e-32: 108: 100.00
+	Ec
		467093 DBHB_ECOLI (3-91): 1.7e-30: 105: 32.58		DBHA_ECOLI (1-89): 2.15e-30: 104: 69.66
+	Ec
		467092 DBHA_ECOLI (3-92): 2.31e-30: 104: 36.67		DBHA_ECOLI (1-89): 2.15e-30: 104: 69.66
+	Nv
		1175388 Q72AX6_NITV2 (3-89): 4.45e-35: 117: 31.03		Q725K7_NITV2 (1-90): 6.02e-24: 88.5: 38.71
+	Nv
		1175753 Q72B43_NITV2 (3-92): 9.82e-30: 103: 36.67		Q72E15_NITV2 (1-89): 1.98e-29: 102: 52.22
+	Nv
		1175754 Q72B43_NITV2 (3-92): 9.82e-30: 103: 36.67		Q72F19_NITV2 (1-90): 2.79e-29: 102: 27.78
+	Mt
		958629 DBH_MYCTU (1-94): 8.08e-27: 99.3: 39.36		DBH_MYCTU (1-90): 8e-25: 93.9: 34.44
+	Nv
		1175389 Q72B43_NITV2 (3-92): 9.82e-30: 103: 36.67		Q725K7_NITV2 (1-90): 6.02e-24: 88.5: 38.71
+	Nv
		1175391 Q72F19_NITV2 (3-91): 6.86e-28: 98.6: 34.83		Q725K7_NITV2 (1-90): 6.02e-24: 88.5: 38.71