HitPredict - High confidence protein-protein interactions

Interactor 1: RPAC1 (P07703)
DNA-directed RNA polymerases I and III subunit RPAC1 (RNA polymerases I and III subunit AC1) (C37) (DNA-directed RNA polymerases I and III 40 kDa polypeptide) (AC40) (C40)
Gene: RPC40

Interactor 2: RPAB5 (P22139)
DNA-directed RNA polymerases I, II, and III subunit RPABC5 (RNA polymerases I, II, and III subunit ABC5) (ABC10-beta) (ABC8) (DNA-directed RNA polymerases I, II, and III 8.3 kDa polypeptide)
Gene: RPB10

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.85	1.00	0.922

Property	Details
Experiments	11805826, 16554755, 37968396, 16429126, 31851481
Identification Methods	tandem affinity purification, affinity chromatography technology, cross-linking study
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	RNA_pol_L~RNA_pol_N
Common GO terms	GO:0003677 - DNA binding GO:0003899 - DNA-directed RNA polymerase activity GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005666 - RNA polymerase III complex and 11 others more... GO:0005736 - RNA polymerase I complex GO:0006360 - transcription by RNA polymerase I GO:0006361 - transcription initiation at RNA polymerase I promoter GO:0006362 - transcription elongation by RNA polymerase I GO:0006363 - termination of RNA polymerase I transcription GO:0006383 - transcription by RNA polymerase III GO:0006384 - transcription initiation at RNA polymerase III promoter GO:0006386 - termination of RNA polymerase III transcription GO:0042254 - ribosome biogenesis GO:0042790 - nucleolar large rRNA transcription by RNA polymerase I GO:0042797 - tRNA transcription by RNA polymerase III
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1	335
Sc

1	70

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Last updated: 11Aug2025