Protein: RPAB5
DNA-directed RNA polymerases I, II, and III subunit RPABC5 (RNA polymerases I, II, and III subunit ABC5) (ABC10-beta) (ABC8) (DNA-directed RNA polymerases I, II, and III 8.3 kDa polypeptide)

Gene: RPAB5, RPB10
Organism: Saccharomyces cerevisiae S288C
Interactions: 97
UniProt ID: P22139

Gene Ontology (top 5):
GO:0001172 - RNA-templated transcription
GO:0003677 - DNA binding
GO:0003899 - DNA-directed RNA polymerase activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

594188

RPB3
DNA-directed RNA polymerase II subunit RPB3

14

4

Small-scale

0.979

High

470461

RPB2
DNA-directed RNA polymerase II subunit RPB2

5

9

Small-scale

0.924

High

459020

RPAC1
DNA-directed RNA polymerases I and III subunit RPAC1

5

4

High-throughput

0.922

High

644867

RPA2
DNA-directed RNA polymerase I subunit RPA135

4

9

Small-scale

0.891

High

645022

RPC2
DNA-directed RNA polymerase III subunit RPC2

4

9

Small-scale

0.881

High

401888

RPB1
DNA-directed RNA polymerase II subunit RPB1

8

11

Small-scale

0.745

High

645071

RPA34
DNA-directed RNA polymerase I subunit RPA34

2

0

High-throughput

0.736

High

534216

RPA1
DNA-directed RNA polymerase I subunit RPA190

6

11

Small-scale

0.730

High

632125

RPAB1
DNA-directed RNA polymerases I, II, and III subunit RPABC1

6

2

Small-scale

0.721

High

632058

RPB4
DNA-directed RNA polymerase II subunit RPB4

5

1

Small-scale

0.706

High

632303

RPAB3
DNA-directed RNA polymerases I, II, and III subunit RPABC3

5

1

Small-scale

0.706

High

645036

RPA12
DNA-directed RNA polymerase I subunit RPA12

4

6

High-throughput

0.694

High

645042

RPB7
DNA-directed RNA polymerase II subunit RPB7

4

4

Small-scale

0.683

High

645052

RPB11
DNA-directed RNA polymerase II subunit RPB11

4

4

Small-scale

0.683

High

645087

RBA50
RNA polymerase II-associated protein RBA50

3

1

High-throughput

0.663

High

645046

RPC8
DNA-directed RNA polymerase III subunit RPC8

3

4

High-throughput

0.662

High

645092

IWR1
RNA polymerase II nuclear localization protein IWR1

4

0

Small-scale

0.661

High

645065

T2FB
Transcription initiation factor IIF subunit beta

4

0

Small-scale

0.653

High

402191

RPC1
DNA-directed RNA polymerase III subunit RPC1

3

11

Small-scale

0.650

High

645029

RPB9
DNA-directed RNA polymerase II subunit RPB9

3

5

Small-scale

0.650

High

645035

RPC3
DNA-directed RNA polymerase III subunit RPC3

3

1

High-throughput

0.650

High

645068

RPA43
DNA-directed RNA polymerase I subunit RPA43

3

1

Small-scale

0.650

High

645057

RTR1
RNA polymerase II subunit B1 CTD phosphatase RTR1

3

1

Small-scale

0.640

High

645064

T2FA
Transcription initiation factor IIF subunit alpha

3

0

High-throughput

0.622

High

645048

RPC5
DNA-directed RNA polymerase III subunit RPC5

1

1

High-throughput

0.618

High

645091

ASR1
Alcohol-sensitive RING finger protein 1

3

0

Small-scale

0.613

High

632228

RPAB2
DNA-directed RNA polymerases I, II, and III subunit RPABC2

2

2

High-throughput

0.601

High

645030

RPAC2
DNA-directed RNA polymerases I and III subunit RPAC2

2

4

High-throughput

0.601

High

645082

RPA49
DNA-directed RNA polymerase I subunit RPA49

2

1

High-throughput

0.601

High

645032

TF3B
Transcription factor IIIB 70 kDa subunit

2

1

High-throughput

0.584

High

645026

RPC4
DNA-directed RNA polymerase III subunit RPC4

2

0

High-throughput

0.576

High

645075

RPA14
DNA-directed RNA polymerase I subunit RPA14

2

0

High-throughput

0.576

High

645073

RPC9
DNA-directed RNA polymerase III subunit RPC9

2

0

Small-scale

0.569

High

645041

SPT4
Transcription elongation factor SPT4

2

0

High-throughput

0.559

High

645043

TAF14
Transcription initiation factor TFIID subunit 14

2

0

Small-scale

0.559

High

645063

DSN1
Kinetochore-associated protein DSN1

2

0

High-throughput

0.559

High

645067

BUD27
Bud site selection protein 27

2

0

Small-scale

0.559

High

645070

SET2
Histone-lysine N-methyltransferase, H3 lysine-36 specific

2

0

High-throughput

0.559

High

645079

H3
Histone H3

2

0

Small-scale

0.559

High

441038

KAPA
cAMP-dependent protein kinase type 1

1

1

High-throughput

0.536

High

441328

KAPB
cAMP-dependent protein kinase type 2

1

1

High-throughput

0.536

High

645056

RSP5
E3 ubiquitin-protein ligase RSP5

1

1

High-throughput

0.536

High

645074

GPN1
GPN-loop GTPase 1

2

4

High-throughput

0.533

High

645058

PSA6
Proteasome subunit alpha type-6

1

1

High-throughput

0.515

High

645025

CG23
G2/mitotic-specific cyclin-3

1

0

High-throughput

0.513

High

645051

KSP1
Serine/threonine-protein kinase KSP1

1

1

High-throughput

0.501

High

444740

SIR2
NAD-dependent histone deacetylase SIR2

1

0

High-throughput

0.493

High

645049

ATR
Serine/threonine-protein kinase MEC1

1

0

High-throughput

0.493

High

583158

CUP2
Transcriptional activator protein CUP2

1

0

High-throughput

0.486

High

517894

SSBP1
Single-stranded nucleic acid-binding protein

1

0

High-throughput

0.480

High

645050

RCK1
Serine/threonine-protein kinase RCK1

1

0

High-throughput

0.480

High

645060

RAD26
DNA repair and recombination protein RAD26

1

0

Small-scale

0.480

High

380969

H2B1
Histone H2B.1

1

1

High-throughput

0.479

High

381403

H2B2
Histone H2B.2

1

1

High-throughput

0.479

High

381874

H4
Histone H4

1

1

High-throughput

0.479

High

561417

TBP
TATA-box-binding protein

1

1

High-throughput

0.479

High

645024

SPT6
Transcription elongation factor SPT6

1

1

High-throughput

0.479

High

645028

SPT5
Transcription elongation factor SPT5

1

1

High-throughput

0.479

High

645031

TF2B
Transcription initiation factor IIB

1

1

High-throughput

0.479

High

645040

RPC6
DNA-directed RNA polymerase III subunit RPC6

1

1

High-throughput

0.479

High

645061

RPAB4
DNA-directed RNA polymerases I, II, and III subunit RPABC4

1

1

High-throughput

0.479

High

645080

SEN1
Helicase SEN1

1

1

High-throughput

0.479

High

645081

CDC14
Tyrosine-protein phosphatase CDC14

1

1

High-throughput

0.479

High

645083

MCE1
mRNA-capping enzyme subunit alpha

1

1

High-throughput

0.479

High

645086

RPC10
DNA-directed RNA polymerase III subunit RPC10

1

6

High-throughput

0.479

High

609175

RPC7
DNA-directed RNA polymerase III subunit RPC7

1

0

High-throughput

0.458

High

645027

KRR1
KRR1 small subunit processome component

1

0

High-throughput

0.458

High

645037

SPT16
FACT complex subunit SPT16

1

0

High-throughput

0.458

High

645039

GSP1
GTP-binding nuclear protein GSP1/CNR1

1

0

High-throughput

0.458

High

645044

SPT10
Protein SPT10

1

0

High-throughput

0.458

High

645045

SPT21
Protein SPT21

1

0

High-throughput

0.458

High

645059

ATAD2
ATPase histone chaperone YTA7

1

0

Small-scale

0.458

High

645066

UTP10
U3 small nucleolar RNA-associated protein 10

1

0

High-throughput

0.458

High

645069

TFC5
Transcription factor TFIIIB component B''

1

0

High-throughput

0.458

High

645076

GIS2
Zinc finger protein GIS2

1

0

High-throughput

0.458

High

645077

APJ1
J domain-containing protein APJ1

1

0

High-throughput

0.458

High

645078

ORC1
Origin recognition complex subunit 1

1

0

High-throughput

0.458

High

645088

POB3
FACT complex subunit POB3

1

0

High-throughput

0.458

High

645090

CDC73
Cell division control protein 73

1

0

High-throughput

0.458

High

645089

GPN3
GPN-loop GTPase 3

1

4

Small-scale

0.437

High

543829

SSB1
Ribosome-associated molecular chaperone SSB1

1

0

High-throughput

0.426

High

645033

HS104
Heat shock protein 104

1

0

High-throughput

0.426

High

645038

MED17
Mediator of RNA polymerase II transcription subunit 17

1

0

Small-scale

0.426

High

645054

CAJ1
Protein CAJ1

1

0

High-throughput

0.426

High

645034

DBF20
Serine/threonine-protein kinase DBF20

1

0

High-throughput

0.279

Low

645093

NOP6
Nucleolar protein 6

1

0

High-throughput

0.279

Low

645023

AIM17
Probable oxidoreductase AIM17

1

0

High-throughput

0.269

Low

645053

HAL5
Serine/threonine-protein kinase HAL5

1

0

High-throughput

0.261

Low

645062

PRK1
Actin-regulating kinase PRK1

1

0

High-throughput

0.261

Low

645084

BCK1
Serine/threonine-protein kinase BCK1/SLK1/SSP31

1

0

High-throughput

0.261

Low

645085

FRK1
Fatty acyl-CoA synthetase and RNA processing-associated kinase 1

1

0

High-throughput

0.261

Low

148860

CET1
mRNA-capping enzyme subunit beta

1

0

High-throughput

0.249

Low

645055

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.249

Low

645072

NET1
Nucleolar protein NET1

1

0

High-throughput

0.249

Low

574849

SAM35
Sorting assembly machinery 35 kDa subunit

1

0

High-throughput

0.238

Low

510199

HSP77
Import motor subunit, mitochondrial

1

0

High-throughput

0.232

Low

645047

LHS1
Heat shock protein 70 homolog LHS1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025