HitPredict

Interactor 1: PROF1 (P07737)
Profilin-1 (Epididymis tissue protein Li 184a) (Profilin I)
Gene: PFN1

Interactor 2: GCC2 (Q8IWJ2)
GRIP and coiled-coil domain-containing protein 2 (185 kDa Golgi coiled-coil protein) (GCC185) (CLL-associated antigen KW-11) (CTCL tumor antigen se1-1) (Ran-binding protein 2-like 4) (RanBP2L4) (Renal carcinoma antigen NY-REN-53)
Gene: GCC2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0016020 - membrane GO:0031267 - small GTPase binding
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 140 Hs			1 1684
+	Hs
		459481 PROF1_HUMAN (1-140): 1.1e-77: 227: 100.00		MYH9_HUMAN (712-1684): 3.25e-42: 172: 11.36
+	Hs
		459576 PROF1_HUMAN (1-140): 1.1e-77: 227: 100.00		GOGA4_HUMAN (602-1682): 2.44e-36: 153: 11.41
+	Hs
		459593 PROF1_HUMAN (1-140): 1.1e-77: 227: 100.00		GOGB1_HUMAN (828-1683): 3.57e-19: 97.3: 9.43
+	Hs
		762454 PROF2_HUMAN (1-140): 1.14e-74: 220: 61.43		GOGB1_HUMAN (828-1683): 3.57e-19: 97.3: 9.43
+	Hs
		459423 PROF1_HUMAN (1-140): 1.1e-77: 227: 100.00		TPR_HUMAN (1127-1683): 4.43e-16: 86.9: 9.75