Interactor 1: RPOA (P0A7Z4)
DNA-directed RNA polymerase subunit alpha (RNAP subunit alpha) (EC 2.7.7.6) (RNA polymerase subunit alpha) (Transcriptase subunit alpha)
Gene: RPOA

Interactor 2: RPOB (P0A8V2)
DNA-directed RNA polymerase subunit beta (RNAP subunit beta) (EC 2.7.7.6) (RNA polymerase subunit beta) (Transcriptase subunit beta)
Gene: RPOB

Species: Escherichia coli K-12

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.62 1.00 0.789

The method score is based on:

Property Details
Experiments 16606699, 15690043
Identification Methods affinity chromatography technology, tandem affinity purification, pull down
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains RNA_pol_A_CTD~RNA_pol_Rpb2_6, RNA_pol_L~RNA_pol_Rpb2_6
Common GO terms GO:0000345 - cytosolic DNA-directed RNA polymerase complex
GO:0003677 - DNA binding
GO:0003899 - DNA-directed 5'-3' RNA polymerase activity
GO:0005737 - cytoplasm
GO:0005829 - cytosol
and 14 others

more...

Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 329
Ec

1 1342
+ Nv
+ Hp
+ Mp
+ Bs

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Last updated: 15 Jul 2024