HitPredict

Interactor 1: UROM (P07911)
Uromodulin (Tamm-Horsfall urinary glycoprotein) (THP) [Cleaved into: Uromodulin, secreted form]
Gene: UMOD

Interactor 2: LEG1 (P09382)
Galectin-1 (Gal-1) (14 kDa laminin-binding protein) (HLBP14) (14 kDa lectin) (Beta-galactoside-binding lectin L-14-I) (Galaptin) (HBL) (HPL) (Lactose-binding lectin 1) (Lectin galactoside-binding soluble 1) (Putative MAPK-activating protein PM12) (S-Lac lectin 1)
Gene: LGALS1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	32045104
Identification Methods	array technology
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005615 - extracellular space GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 640 Hs			1 135
+	Hs
		462739 UROM_HUMAN (1-621): 1.51e-109: 345: 100.00		LEG3_HUMAN (3-134): 1.12e-48: 158: 28.47
+	Hs
		425699 UROM_HUMAN (1-621): 1.51e-109: 345: 100.00		LEG2_HUMAN (1-135): 7.38e-42: 136: 42.22
+	Hs
		480708 TENA_HUMAN (62-455): 1.94e-41: 164: 10.40		LEG1_HUMAN (1-135): 1.21e-53: 166: 100.00
+	Hs
		609582 TENA_HUMAN (62-455): 1.94e-41: 164: 10.40		LEG3_HUMAN (3-134): 1.12e-48: 158: 28.47
+	Hs
		480702 FBLN1_HUMAN (20-244): 4.27e-27: 118: 23.48		LEG1_HUMAN (1-135): 1.21e-53: 166: 100.00
+	Hs
		609575 FBLN1_HUMAN (20-244): 4.27e-27: 118: 23.48		LEG3_HUMAN (3-134): 1.12e-48: 158: 28.47
+	Hs
		480769 NOTC2_HUMAN (8-313): 4.82e-22: 103: 15.57		LEG1_HUMAN (1-135): 1.21e-53: 166: 100.00
+	Hs
		480914 TEN3_HUMAN (2-167): 3.82e-21: 101: 16.30		LEG1_HUMAN (1-135): 1.21e-53: 166: 100.00
+	Hs
		480790 NID2_HUMAN (35-148): 1.04e-18: 92.8: 34.15		LEG1_HUMAN (1-135): 1.21e-53: 166: 100.00
+	Hs
		480677 NID1_HUMAN (35-170): 3.04e-16: 85.1: 36.24		LEG1_HUMAN (1-135): 1.21e-53: 166: 100.00
+	Hs
		609676 NID2_HUMAN (35-148): 1.04e-18: 92.8: 34.15		LEG3_HUMAN (3-134): 1.12e-48: 158: 28.47
+	Hs
		125235 FBLN1_HUMAN (20-244): 4.27e-27: 118: 23.48		LEG9_HUMAN (10-133): 1.51e-35: 126: 31.50
+	Hs
		572678 NID1_HUMAN (35-170): 3.04e-16: 85.1: 36.24		LEG3_HUMAN (3-134): 1.12e-48: 158: 28.47
+	Hs
		480907 TEN2_HUMAN (291-448): 2.75e-12: 72.6: 12.35		LEG1_HUMAN (1-135): 1.21e-53: 166: 100.00
+	Mm
		1298023 CUBN_MOUSE (248-454): 9.19e-15: 80.4: 10.00		Q8C253_MOUSE (3-133): 7e-49: 158: 28.68
+	Hs
		868688 NID2_HUMAN (35-148): 1.04e-18: 92.8: 34.15		LEG7_HUMAN (1-132): 4.87e-45: 145: 33.58
+	Hs
		480825 TEN4_HUMAN (290-448): 1.75e-11: 70: 11.11		LEG1_HUMAN (1-135): 1.21e-53: 166: 100.00
+	Hs
		125448 NID2_HUMAN (35-148): 1.04e-18: 92.8: 34.15		LEG9_HUMAN (10-133): 1.51e-35: 126: 31.50
+	Hs
		125198 NID1_HUMAN (35-170): 3.04e-16: 85.1: 36.24		LEG9_HUMAN (10-133): 1.51e-35: 126: 31.50
+	Hs
		940782 TEN4_HUMAN (290-448): 1.75e-11: 70: 11.11		LEG4_HUMAN (5-134): 2.63e-36: 128: 26.28