Protein: RBBP5
Retinoblastoma-binding protein 5 (RBBP-5) (Retinoblastoma-binding protein RBQ-3)

Gene: RBBP5
Organism: Homo sapiens
Interactions: 226
UniProt ID: Q15291

Gene Ontology (top 5):
GO:0000976 - transcription cis-regulatory region binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005730 - nucleolus
GO:0006974 - DNA damage response

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

903242

WDR5
WD repeat-containing protein 5

36

18

Small-scale

0.994

High

975258

KMT2A
Histone-lysine N-methyltransferase 2A

15

20

Small-scale

0.986

High

165680

SET1A
Histone-lysine N-methyltransferase SETD1A

17

20

Small-scale

0.985

High

152650

KMT2D
Histone-lysine N-methyltransferase 2D

16

20

Small-scale

0.983

High

1070746

KMT2C
Histone-lysine N-methyltransferase 2C

11

20

Small-scale

0.978

High

1070809

SET1B
Histone-lysine N-methyltransferase SETD1B

9

20

Small-scale

0.972

High

183118

KDM6A
Lysine-specific demethylase 6A

9

18

Small-scale

0.969

High

1070808

KMT2B
Histone-lysine N-methyltransferase 2B

9

20

Small-scale

0.967

High

1070728

WDR82
WD repeat-containing protein 82

5

19

Small-scale

0.915

High

1070712

RBBP5
Retinoblastoma-binding protein 5

2

18

Small-scale

0.799

High

1070799

ASH2L
Set1/Ash2 histone methyltransferase complex subunit ASH2

29

18

Small-scale

0.769

High

1070794

CXXC1
CXXC-type zinc finger protein 1

14

20

Small-scale

0.761

High

1057759

NCOA6
Nuclear receptor coactivator 6

10

20

Small-scale

0.758

High

1070730

PAXI1
PAX-interacting protein 1

7

18

Small-scale

0.746

High

1070769

DPY30
Protein dpy-30 homolog

7

5

Small-scale

0.740

High

1070817

HCFC2
Host cell factor 2

6

9

Small-scale

0.729

High

848222

HCFC1
Host cell factor 1

6

8

Small-scale

0.724

High

122775

MEN1
Menin

6

4

Small-scale

0.719

High

1070747

BD1L1
Biorientation of chromosomes in cell division protein 1-like 1

5

20

High-throughput

0.714

High

150102

UTY
Histone demethylase UTY

1

18

High-throughput

0.691

High

681858

AKT1
RAC-alpha serine/threonine-protein kinase

1

5

High-throughput

0.691

High

1039579

SNW1
SNW domain-containing protein 1

1

4

High-throughput

0.691

High

1070715

DDB1
DNA damage-binding protein 1

1

11

Small-scale

0.691

High

174908

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

4

13

Small-scale

0.683

High

369650

ESR1
Estrogen receptor

4

20

Small-scale

0.683

High

386777

P53
Cellular tumor antigen p53

3

5

Small-scale

0.680

High

900166

RL37A
Large ribosomal subunit protein eL43

3

2

High-throughput

0.667

High

1070766

PAGR1
PAXIP1-associated glutamate-rich protein 1

3

1

Small-scale

0.662

High

1070787

MBIP1
MAP3K12-binding inhibitory protein 1

3

3

High-throughput

0.656

High

717102

CTNB1
Catenin beta-1

3

8

Small-scale

0.651

High

930225

UBC9
SUMO-conjugating enzyme UBC9

1

1

Small-scale

0.647

High

1070783

CHD8
Chromodomain-helicase-DNA-binding protein 8

2

18

Small-scale

0.646

High

1070777

KAT8
Histone acetyltransferase KAT8

2

6

Small-scale

0.621

High

1070727

WDR59
GATOR2 complex protein WDR59

1

19

High-throughput

0.618

High

1070735

URP2
Fermitin family homolog 3

1

1

High-throughput

0.618

High

1070758

WDR24
GATOR2 complex protein WDR24

1

19

High-throughput

0.618

High

211187

BUB3
Mitotic checkpoint protein BUB3

1

19

High-throughput

0.618

High

1070720

ZC3HD
Zinc finger CCCH domain-containing protein 13

1

20

High-throughput

0.618

High

1070748

NUP43
Nucleoporin Nup43

1

19

High-throughput

0.618

High

1070750

DCAF4
DDB1- and CUL4-associated factor 4

1

1

High-throughput

0.618

High

1070778

CSR2B
Cysteine-rich protein 2-binding protein

1

11

High-throughput

0.618

High

1070779

WDR76
WD repeat-containing protein 76

1

19

High-throughput

0.618

High

1070788

DCA13
DDB1- and CUL4-associated factor 13

1

19

High-throughput

0.618

High

1070789

FANCI
Fanconi anemia group I protein

1

1

High-throughput

0.618

High

1070795

UBP36
Ubiquitin carboxyl-terminal hydrolase 36

1

7

High-throughput

0.618

High

934185

CSK21
Casein kinase II subunit alpha

2

11

High-throughput

0.611

High

996684

SSRP1
FACT complex subunit SSRP1

2

20

High-throughput

0.611

High

1070719

CYTSB
Cytospin-B

2

11

High-throughput

0.611

High

1070744

RB15B
Putative RNA-binding protein 15B

2

9

High-throughput

0.611

High

1070755

BOD1
Biorientation of chromosomes in cell division protein 1

2

3

High-throughput

0.611

High

1070798

RERE
Arginine-glutamic acid dipeptide repeats protein

2

16

High-throughput

0.611

High

1070812

KDM2A
Lysine-specific demethylase 2A

2

12

High-throughput

0.611

High

740526

PPARG
Peroxisome proliferator-activated receptor gamma

2

17

Small-scale

0.594

High

426648

H10
Histone H1.0

2

0

High-throughput

0.585

High

227515

PRKN
E3 ubiquitin-protein ligase parkin

2

18

High-throughput

0.584

High

607819

USF1
Upstream stimulatory factor 1

2

20

Small-scale

0.584

High

818071

SOX2
Transcription factor SOX-2

2

18

Small-scale

0.584

High

917305

H4
Histone H4

2

7

High-throughput

0.584

High

934787

H31
Histone H3.1

2

15

High-throughput

0.584

High

998731

EP300
Histone acetyltransferase p300

2

19

Small-scale

0.584

High

1070733

KANL1
KAT8 regulatory NSL complex subunit 1

2

4

Small-scale

0.584

High

1070752

CBP
CREB-binding protein

2

17

Small-scale

0.584

High

1070807

YETS2
YEATS domain-containing protein 2

2

15

High-throughput

0.584

High

1070724

PKHA7
Pleckstrin homology domain-containing family A member 7

1

17

High-throughput

0.575

High

1070736

WDR5B
WD repeat-containing protein 5B

1

19

Small-scale

0.575

High

1070764

PYGO2
Pygopus homolog 2

1

1

Small-scale

0.561

High

1070776

ZN335
Zinc finger protein 335

1

3

Small-scale

0.554

High

148846

CTRO
Citron Rho-interacting kinase

1

7

High-throughput

0.553

High

1070729

TRI67
Tripartite motif-containing protein 67

1

11

High-throughput

0.553

High

1070775

PKHA4
Pleckstrin homology domain-containing family A member 4

1

14

High-throughput

0.553

High

182162

PDPK1
3-phosphoinositide-dependent protein kinase 1

1

4

High-throughput

0.536

High

470031

H2AZ
Histone H2A.Z

1

11

High-throughput

0.536

High

508540

TOP1
DNA topoisomerase 1

1

3

High-throughput

0.536

High

536522

IRF2
Interferon regulatory factor 2

1

1

High-throughput

0.536

High

564911

HMGA1
High mobility group protein HMG-I/HMG-Y

1

2

High-throughput

0.536

High

586764

CSK22
Casein kinase II subunit alpha'

1

9

High-throughput

0.536

High

801158

KI67
Proliferation marker protein Ki-67

1

16

High-throughput

0.536

High

830366

KC1E
Casein kinase I isoform epsilon

1

9

High-throughput

0.536

High

858626

PPP5
Serine/threonine-protein phosphatase 5

1

5

High-throughput

0.536

High

869466

ATN1
Atrophin-1

1

17

High-throughput

0.536

High

885126

SESN2
Sestrin-2

1

1

High-throughput

0.536

High

931647

CSK2B
Casein kinase II subunit beta

1

2

High-throughput

0.536

High

948797

HMGN5
High mobility group nucleosome-binding domain-containing protein 5

1

4

High-throughput

0.536

High

964185

FOXK2
Forkhead box protein K2

1

4

High-throughput

0.536

High

1042998

CUL4A
Cullin-4A

1

20

Small-scale

0.536

High

1043360

CUL4B
Cullin-4B

1

20

Small-scale

0.536

High

1061117

NUMA1
Nuclear mitotic apparatus protein 1

1

16

High-throughput

0.536

High

1070718

H2B2E
Histone H2B type 2-E

1

10

High-throughput

0.536

High

1070734

EMSY
BRCA2-interacting transcriptional repressor EMSY

1

20

Small-scale

0.536

High

1070751

DYRK2
Dual specificity tyrosine-phosphorylation-regulated kinase 2

1

14

High-throughput

0.536

High

1070760

CDC5L
Cell division cycle 5-like protein

1

9

High-throughput

0.536

High

1070763

ASCL2
Achaete-scute homolog 2

1

2

Small-scale

0.536

High

1070770

FOXQ1
Forkhead box protein Q1

1

4

High-throughput

0.536

High

1070772

NUCKS
Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1

1

2

High-throughput

0.536

High

1070784

E41L5
Band 4.1-like protein 5

1

4

High-throughput

0.536

High

1070791

MIOS
GATOR2 complex protein MIOS

1

7

High-throughput

0.536

High

1070803

TBK1
Serine/threonine-protein kinase TBK1

1

7

High-throughput

0.536

High

1070726

CDC73
Parafibromin

1

0

Small-scale

0.513

High

1032416

CTBP1
C-terminal-binding protein 1

1

6

High-throughput

0.508

High

414294

RB
Retinoblastoma-associated protein

1

3

Small-scale

0.501

High

890675

PTEN
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

1

4

High-throughput

0.501

High

1070717

H31T
Histone H3.1t

1

15

Small-scale

0.501

High

1070731

H32
Histone H3.2

1

15

Small-scale

0.501

High

64595

MYH7B
Myosin-7B

1

5

High-throughput

0.489

High

537742

INSRR
Insulin receptor-related protein

1

5

High-throughput

0.489

High

1070740

MICU2
Calcium uptake protein 2, mitochondrial

1

2

High-throughput

0.489

High

1070786

DISC1
Disrupted in schizophrenia 1 protein

1

2

High-throughput

0.489

High

136018

ACACB
Acetyl-CoA carboxylase 2

1

13

High-throughput

0.479

High

146225

ARI1A
AT-rich interactive domain-containing protein 1A

1

15

High-throughput

0.479

High

165853

KDM6B
Lysine-specific demethylase 6B

1

20

Small-scale

0.479

High

171030

TBXT
T-box transcription factor T

1

4

High-throughput

0.479

High

197711

CRX
Cone-rod homeobox protein

1

7

High-throughput

0.479

High

237395

CCNT2
Cyclin-T2

1

3

High-throughput

0.479

High

242471

DKC1
H/ACA ribonucleoprotein complex subunit DKC1

1

4

High-throughput

0.479

High

244472

BRD4
Bromodomain-containing protein 4

1

16

High-throughput

0.479

High

266020

PSIP1
PC4 and SFRS1-interacting protein

1

10

High-throughput

0.479

High

294855

RECQ4
ATP-dependent DNA helicase Q4

1

20

High-throughput

0.479

High

301141

KDM4B
Lysine-specific demethylase 4B

1

4

Small-scale

0.479

High

345440

FOS
Protein c-Fos

1

6

High-throughput

0.479

High

346841

MYC
Myc proto-oncogene protein

1

20

High-throughput

0.479

High

391714

H2A1B
Histone H2A type 1-B/E

1

8

High-throughput

0.479

High

416433

S10A9
Protein S100-A9

1

3

High-throughput

0.479

High

486786

MYB
Transcriptional activator Myb

1

9

Small-scale

0.479

High

487455

ANDR
Androgen receptor

1

18

High-throughput

0.479

High

489056

H14
Histone H1.4

1

13

High-throughput

0.479

High

495532

THIO
Thioredoxin

1

8

High-throughput

0.479

High

505218

EGR2
E3 SUMO-protein ligase EGR2

1

3

High-throughput

0.479

High

509007

TOP2A
DNA topoisomerase 2-alpha

1

7

High-throughput

0.479

High

545975

MYOD1
Myoblast determination protein 1

1

2

High-throughput

0.479

High

551715

DESP
Desmoplakin

1

19

High-throughput

0.479

High

598130

FLNA
Filamin-A

1

14

High-throughput

0.479

High

620351

GATA2
Endothelial transcription factor GATA-2

1

6

High-throughput

0.479

High

632738

TYY1
Transcriptional repressor protein YY1

1

6

High-throughput

0.479

High

637892

PSA3
Proteasome subunit alpha type-3

1

5

Small-scale

0.479

High

641414

PAX6
Paired box protein Pax-6

1

3

High-throughput

0.479

High

672838

CDC27
Cell division cycle protein 27 homolog

1

8

Small-scale

0.479

High

692138

ELF1
ETS-related transcription factor Elf-1

1

12

High-throughput

0.479

High

707640

H2B1B
Histone H2B type 1-B

1

10

High-throughput

0.479

High

727521

HNF1B
Hepatocyte nuclear factor 1-beta

1

7

High-throughput

0.479

High

749518

BRCA1
Breast cancer type 1 susceptibility protein

1

7

High-throughput

0.479

High

773380

RL13A
Large ribosomal subunit protein uL13

1

5

High-throughput

0.479

High

782547

HNF4A
Hepatocyte nuclear factor 4-alpha

1

14

High-throughput

0.479

High

785363

ELK3
ETS domain-containing protein Elk-3

1

10

High-throughput

0.479

High

790674

WASP
Actin nucleation-promoting factor WAS

1

10

Small-scale

0.479

High

839744

LHX2
LIM/homeobox protein Lhx2

1

1

High-throughput

0.479

High

848038

MECP2
Methyl-CpG-binding protein 2

1

3

High-throughput

0.479

High

853299

IMA1
Importin subunit alpha-1

1

3

High-throughput

0.479

High

867597

BLM
RecQ-like DNA helicase BLM

1

20

High-throughput

0.479

High

884157

KLF3
Krueppel-like factor 3

1

14

High-throughput

0.479

High

918380

H2B1C
Histone H2B type 1-C/E/F/G/I

1

10

High-throughput

0.479

High

920468

RS25
Small ribosomal subunit protein eS25

1

3

High-throughput

0.479

High

950187

SMAD3
Mothers against decapentaplegic homolog 3

1

3

Small-scale

0.479

High

952352

H33
Histone H3.3

1

15

High-throughput

0.479

High

964335

RUNX1
Runt-related transcription factor 1

1

1

High-throughput

0.479

High

971180

H11
Histone H1.1

1

13

High-throughput

0.479

High

988764

PAX8
Paired box protein Pax-8

1

4

High-throughput

0.479

High

1029448

TIF1B
Transcription intermediary factor 1-beta

1

14

High-throughput

0.479

High

1032291

PPIL2
RING-type E3 ubiquitin-protein ligase PPIL2

1

4

High-throughput

0.479

High

1034058

TCOF
Treacle protein

1

20

High-throughput

0.479

High

1035768

BIRC3
Baculoviral IAP repeat-containing protein 3

1

4

High-throughput

0.479

High

1041623

CUL3
Cullin-3

1

20

High-throughput

0.479

High

1045590

NOG2
Nucleolar GTP-binding protein 2

1

10

High-throughput

0.479

High

1046687

KLF5
Krueppel-like factor 5

1

11

High-throughput

0.479

High

1055122

HLTF
Helicase-like transcription factor

1

12

High-throughput

0.479

High

1059530

KIF22
Kinesin-like protein KIF22

1

4

High-throughput

0.479

High

1060289

NFIX
Nuclear factor 1 X-type

1

12

High-throughput

0.479

High

1065793

RRS1
Ribosome biogenesis regulatory protein homolog

1

3

High-throughput

0.479

High

1070713

ELF2
ETS-related transcription factor Elf-2

1

8

High-throughput

0.479

High

1070714

SMAD2
Mothers against decapentaplegic homolog 2

1

3

Small-scale

0.479

High

1070716

TBR1
T-box brain protein 1

1

4

High-throughput

0.479

High

1070723

MAP1S
Microtubule-associated protein 1S

1

9

High-throughput

0.479

High

1070725

IFIX
Pyrin and HIN domain-containing protein 1

1

7

High-throughput

0.479

High

1070737

P66A
Transcriptional repressor p66-alpha

1

2

High-throughput

0.479

High

1070738

TF2LX
Homeobox protein TGIF2LX

1

4

High-throughput

0.479

High

1070739

ZZZ3
ZZ-type zinc finger-containing protein 3

1

2

High-throughput

0.479

High

1070741

CCAR2
Cell cycle and apoptosis regulator protein 2

1

2

Small-scale

0.479

High

1070742

SIR6
NAD-dependent protein deacylase sirtuin-6

1

4

High-throughput

0.479

High

1070743

Z280C
Zinc finger protein 280C

1

7

High-throughput

0.479

High

1070745

TNR6A
Trinucleotide repeat-containing gene 6A protein

1

19

Small-scale

0.479

High

1070749

MAFA
Transcription factor MafA

1

7

Small-scale

0.479

High

1070754

MCRS1
Microspherule protein 1

1

2

High-throughput

0.479

High

1070756

H2A1H
Histone H2A type 1-H

1

8

High-throughput

0.479

High

1070757

ZN512
Zinc finger protein 512

1

2

High-throughput

0.479

High

1070759

MINT
Msx2-interacting protein

1

9

High-throughput

0.479

High

1070761

ELF4
ETS-related transcription factor Elf-4

1

9

High-throughput

0.479

High

1070762

PRP18
Pre-mRNA-splicing factor 18

1

1

High-throughput

0.479

High

1070765

GPTC1
G patch domain-containing protein 1

1

8

High-throughput

0.479

High

1070767

PAPOG
Poly(A) polymerase gamma

1

2

High-throughput

0.479

High

1070768

MK67I
MKI67 FHA domain-interacting nucleolar phosphoprotein

1

11

High-throughput

0.479

High

1070771

NAT10
RNA cytidine acetyltransferase

1

2

Small-scale

0.479

High

1070773

BACD3
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3

1

6

Small-scale

0.479

High

1070774

SENP3
Sentrin-specific protease 3

1

7

Small-scale

0.479

High

1070780

KANL2
KAT8 regulatory NSL complex subunit 2

1

2

High-throughput

0.479

High

1070781

NANOG
Homeobox protein NANOG

1

7

High-throughput

0.479

High

1070782

ZN532
Zinc finger protein 532

1

2

High-throughput

0.479

High

1070785

INCE
Inner centromere protein

1

17

High-throughput

0.479

High

1070790

DDX18
ATP-dependent RNA helicase DDX18

1

20

High-throughput

0.479

High

1070792

TLS1
Splicing factor C9orf78

1

1

High-throughput

0.479

High

1070796

CHD7
Chromodomain-helicase-DNA-binding protein 7

1

18

Small-scale

0.479

High

1070797

KANL3
KAT8 regulatory NSL complex subunit 3

1

3

High-throughput

0.479

High

1070800

LHX3
LIM/homeobox protein Lhx3

1

1

High-throughput

0.479

High

1070801

POLK
DNA polymerase kappa

1

1

High-throughput

0.479

High

1070802

ZRAN1
Ubiquitin thioesterase ZRANB1

1

5

High-throughput

0.479

High

1070804

BAZ2B
Bromodomain adjacent to zinc finger domain protein 2B

1

20

High-throughput

0.479

High

1070805

AGO2
Protein argonaute-2

1

2

Small-scale

0.479

High

1070806

MED23
Mediator of RNA polymerase II transcription subunit 23

1

2

High-throughput

0.479

High

1070810

SRRM2
Serine/arginine repetitive matrix protein 2

1

20

High-throughput

0.479

High

1070813

NOP58
Nucleolar protein 58

1

7

High-throughput

0.479

High

1070814

KDM3A
Lysine-specific demethylase 3A

1

4

High-throughput

0.479

High

1070815

SP16H
FACT complex subunit SPT16

1

6

High-throughput

0.479

High

1070816

MAFB
Transcription factor MafB

1

14

Small-scale

0.479

High

658505

TEAD1
Transcriptional enhancer factor TEF-1

1

0

High-throughput

0.458

High

1053332

FRG1
Protein FRG1

1

0

High-throughput

0.458

High

1059582

MEF2D
Myocyte-specific enhancer factor 2D

1

0

Small-scale

0.458

High

1070818

MORC2
ATPase MORC2

1

0

High-throughput

0.458

High

1070732

TBA1A
Tubulin alpha-1A chain

1

9

Small-scale

0.445

High

1070793

GRHL1
Grainyhead-like protein 1 homolog

1

3

High-throughput

0.445

High

322665

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

13

High-throughput

0.437

High

400562

RLA2
Large ribosomal subunit protein P2

1

2

High-throughput

0.437

High

865142

SMTN
Smoothelin

1

8

High-throughput

0.437

High

1070721

KPRP
Keratinocyte proline-rich protein

1

2

High-throughput

0.437

High

1070722

RN123
E3 ubiquitin-protein ligase RNF123

1

12

High-throughput

0.437

High

1070753

ANKR9
Ankyrin repeat domain-containing protein 9

1

0

High-throughput

0.279

Low

1014272

BST2
Bone marrow stromal antigen 2

1

0

High-throughput

0.269

Low

1070811

ITM2B
Integral membrane protein 2B

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024