Protein: FBLN1
Fibulin-1 (FIBL-1)

Gene: FBLN1
Organism: Homo sapiens
Interactions: 147
UniProt ID: P23142

Gene Ontology (top 5):
GO:0001933 - negative regulation of protein phosphorylation
GO:0001968 - fibronectin binding
GO:0005178 - integrin binding
GO:0005201 - extracellular matrix structural constituent
GO:0005509 - calcium ion binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

572680

NID1
Nidogen-1

3

6

Small-scale

0.845

High

654494

FBLN3
EGF-containing fibulin-like extracellular matrix protein 1

2

19

High-throughput

0.811

High

654544

NELL1
Protein kinase C-binding protein NELL1

2

20

High-throughput

0.811

High

654548

LIGO1
Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1

2

4

High-throughput

0.783

High

654492

NOTC2
Neurogenic locus notch homolog protein 2

2

17

High-throughput

0.776

High

654500

PTPRK
Receptor-type tyrosine-protein phosphatase kappa

3

2

High-throughput

0.770

High

389032

FINC
Fibronectin

2

9

Small-scale

0.767

High

654529

TRI42
Tripartite motif-containing protein 42

2

20

High-throughput

0.700

High

437626

HEPS
Serine protease hepsin

1

17

High-throughput

0.691

High

654563

FBLN5
Fibulin-5

1

19

High-throughput

0.691

High

654574

ST14
Suppressor of tumorigenicity 14 protein

1

16

High-throughput

0.691

High

421513

A4
Amyloid-beta precursor protein

3

9

Small-scale

0.674

High

125235

LEG9
Galectin-9

3

14

High-throughput

0.667

High

654560

PLS4
Phospholipid scramblase 4

3

3

High-throughput

0.667

High

654468

FBLN1
Fibulin-1

1

19

Small-scale

0.647

High

144079

WNT7A
Protein Wnt-7a

2

20

High-throughput

0.628

High

654485

DEF1
Neutrophil defensin 1

2

3

High-throughput

0.628

High

654503

OCLN
Occludin

2

5

High-throughput

0.628

High

654526

TAFA3
Chemokine-like protein TAFA-3

2

6

High-throughput

0.628

High

654569

COLQ
Acetylcholinesterase collagenic tail peptide

2

3

High-throughput

0.628

High

654534

LTBP4
Latent-transforming growth factor beta-binding protein 4

1

19

High-throughput

0.621

High

654568

NOTC3
Neurogenic locus notch homolog protein 3

1

19

High-throughput

0.621

High

654506

LRAD1
Low-density lipoprotein receptor class A domain-containing protein 1

1

16

High-throughput

0.618

High

136830

AGRIN
Agrin [Cleaved into: Agrin N-terminal 110 kDa subunit; Agrin C-terminal 110 kDa subunit; Agrin C-terminal 90 kDa fragment

1

19

High-throughput

0.618

High

543410

PSG1
Pregnancy-specific beta-1-glycoprotein 1

1

11

High-throughput

0.618

High

654501

PSG3
Pregnancy-specific beta-1-glycoprotein 3

1

13

High-throughput

0.618

High

654477

HXA1
Homeobox protein Hox-A1

3

19

High-throughput

0.609

High

654537

ZFP41
Zinc finger protein 41 homolog

3

20

High-throughput

0.609

High

221317

SPY1
Protein sprouty homolog 1

2

5

High-throughput

0.606

High

654475

CXCL5
C-X-C motif chemokine 5

2

2

High-throughput

0.606

High

654491

CREB5
Cyclic AMP-responsive element-binding protein 5

2

7

High-throughput

0.606

High

192061

PA2GX
Group 10 secretory phospholipase A2

2

0

High-throughput

0.602

High

456937

CO8A
Complement component C8 alpha chain

1

14

High-throughput

0.575

High

654552

EGFL8
Epidermal growth factor-like protein 8

1

19

High-throughput

0.575

High

654564

EGFL7
Epidermal growth factor-like protein 7

1

19

High-throughput

0.575

High

654518

TYW3
tRNA wybutosine-synthesizing protein 3 homolog

2

1

High-throughput

0.574

High

654523

ZN517
Zinc finger protein 517

2

20

High-throughput

0.574

High

654562

PAK5
Serine/threonine-protein kinase PAK 5

2

5

High-throughput

0.574

High

654480

RM12
Large ribosomal subunit protein bL12m

2

1

High-throughput

0.553

High

654490

PAX5
Paired box protein Pax-5

2

1

High-throughput

0.553

High

654504

KR192
Keratin-associated protein 19-2

2

1

High-throughput

0.553

High

654507

LCE1C
Late cornified envelope protein 1C

2

4

High-throughput

0.553

High

654510

LCE1A
Late cornified envelope protein 1A

2

1

High-throughput

0.553

High

654511

LCE1B
Late cornified envelope protein 1B

2

3

High-throughput

0.553

High

654513

LCE3A
Late cornified envelope protein 3A

2

3

High-throughput

0.553

High

654528

KR111
Keratin-associated protein 11-1

2

1

High-throughput

0.553

High

387235

APOA1
Apolipoprotein A-I

1

4

High-throughput

0.541

High

561343

TDGF1
Protein Cripto

1

4

High-throughput

0.541

High

654488

SMAD3
Mothers against decapentaplegic homolog 3

1

9

High-throughput

0.541

High

128579

AGRP
Agouti-related protein

1

1

High-throughput

0.536

High

342510

LY86
Lymphocyte antigen 86

1

2

High-throughput

0.536

High

654471

CALX
Calnexin

1

9

High-throughput

0.536

High

654483

SLUR1
Secreted Ly-6/uPAR-related protein 1

1

2

High-throughput

0.536

High

654495

MFAP5
Microfibrillar-associated protein 5

1

5

High-throughput

0.536

High

654498

EP3A
Epididymal secretory protein E3-alpha

1

1

High-throughput

0.536

High

654520

IGFL1
Insulin growth factor-like family member 1

1

8

High-throughput

0.536

High

654521

IGFL3
Insulin growth factor-like family member 3

1

8

High-throughput

0.536

High

654536

DB125
Beta-defensin 125

1

1

High-throughput

0.536

High

654546

ESPB1
Epididymal sperm-binding protein 1

1

13

High-throughput

0.536

High

654553

C1QT7
Complement C1q tumor necrosis factor-related protein 7

1

10

High-throughput

0.536

High

654476

CCN3
CCN family member 3

1

9

Small-scale

0.527

High

654524

KCTD9
BTB/POZ domain-containing protein KCTD9

2

5

High-throughput

0.521

High

654541

LPD6B
Ly6/PLAUR domain-containing protein 6B

1

0

High-throughput

0.513

High

654496

SMAD4
Mothers against decapentaplegic homolog 4

1

9

High-throughput

0.508

High

387789

FIBB
Fibrinogen beta chain [Cleaved into: Fibrinopeptide B; Fibrinogen beta chain]

1

8

Small-scale

0.501

High

584613

ELN
Elastin

1

10

Small-scale

0.501

High

654472

CCN2
CCN family member 2

1

9

Small-scale

0.501

High

654479

FXR1
RNA-binding protein FXR1

1

1

High-throughput

0.494

High

654525

NUFP2
FMR1-interacting protein NUFIP2

1

12

High-throughput

0.494

High

654545

TANK
TRAF family member-associated NF-kappa-B activator

1

1

High-throughput

0.494

High

654533

ZN444
Zinc finger protein 444

1

20

High-throughput

0.489

High

654538

CCD89
Coiled-coil domain-containing protein 89

1

4

High-throughput

0.489

High

654547

ZN707
Zinc finger protein 707

1

20

High-throughput

0.489

High

654549

ZN764
Zinc finger protein 764

1

20

High-throughput

0.489

High

654559

FBX6
F-box only protein 6

1

20

High-throughput

0.489

High

555454

SKIL
Ski-like protein

1

0

High-throughput

0.486

High

180480

PLS1
Phospholipid scramblase 1

1

6

High-throughput

0.481

High

654470

1433T
14-3-3 protein theta

1

3

High-throughput

0.481

High

654493

PPARA
Peroxisome proliferator-activated receptor alpha

1

9

High-throughput

0.481

High

654522

ATL4
ADAMTS-like protein 4

1

12

High-throughput

0.481

High

654527

ATL2
ADAMTS-like protein 2

1

12

High-throughput

0.481

High

141986

FCN1
Ficolin-1

1

9

High-throughput

0.479

High

321714

DKK1
Dickkopf-related protein 1

1

2

High-throughput

0.479

High

370153

CYTN
Cystatin-SN

1

6

Small-scale

0.479

High

590805

TIMP2
Metalloproteinase inhibitor 2

1

7

High-throughput

0.479

High

654469

PSA1
Proteasome subunit alpha type-1

1

1

High-throughput

0.479

High

654484

WNT4
Protein Wnt-4

1

20

High-throughput

0.479

High

654497

CUL3
Cullin-3

1

20

High-throughput

0.479

High

654516

SFRP4
Secreted frizzled-related protein 4

1

2

High-throughput

0.479

High

654481

ATX3
Ataxin-3

1

1

High-throughput

0.470

High

654517

Q6FHY5
MEOX2 protein

1

6

High-throughput

0.470

High

139684

CAC1A
Voltage-dependent P/Q-type calcium channel subunit alpha-1A

1

14

High-throughput

0.464

High

654482

ATN1
Atrophin-1

1

16

High-throughput

0.464

High

654515

GFI1B
Zinc finger protein Gfi-1b

1

20

High-throughput

0.464

High

654561

NLGN3
Neuroligin-3

1

5

Small-scale

0.464

High

561107

GILT
Gamma-interferon-inducible lysosomal thiol reductase

1

0

High-throughput

0.458

High

654487

H31
Histone H3.1

1

0

High-throughput

0.458

High

431514

AP2A
Transcription factor AP-2-alpha

1

10

High-throughput

0.457

High

654542

HTRA1
Serine protease HTRA1

1

10

Small-scale

0.457

High

167435

WNT9A
Protein Wnt-9a

1

20

High-throughput

0.445

High

346757

CER1
Cerberus

1

5

High-throughput

0.445

High

388493

CRP

1

1

High-throughput

0.445

High

404670

PRIO
Major prion protein

1

1

High-throughput

0.445

High

480702

LEG1
Galectin-1

1

14

High-throughput

0.445

High

555203

ECP
Eosinophil cationic protein

1

3

High-throughput

0.445

High

609575

LEG3
Galectin-3

1

14

High-throughput

0.445

High

654530

FA20C
Extracellular serine/threonine protein kinase FAM20C

1

1

Small-scale

0.445

High

654570

ITM2B
Integral membrane protein 2B

1

1

High-throughput

0.445

High

654478

MEOX2
Homeobox protein MOX-2

1

7

High-throughput

0.439

High

654502

TAF9
Transcription initiation factor TFIID subunit 9

1

2

High-throughput

0.439

High

654519

EDC4
Enhancer of mRNA-decapping protein 4

1

2

High-throughput

0.439

High

654531

DDIAS
DNA damage-induced apoptosis suppressor protein

1

1

Small-scale

0.439

High

654540

NEDD1
Protein NEDD1

1

3

High-throughput

0.439

High

654557

TF7L2
Transcription factor 7-like 2

1

5

High-throughput

0.439

High

654571

KLH20
Kelch-like protein 20

1

1

Small-scale

0.439

High

105345

APRIO
Alternative prion protein

1

3

High-throughput

0.437

High

217837

TGON2
Trans-Golgi network integral membrane protein 2

1

18

High-throughput

0.437

High

654486

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

1

High-throughput

0.437

High

654554

HOIL1
RanBP-type and C3HC4-type zinc finger-containing protein 1

1

6

High-throughput

0.437

High

654565

XPO7
Exportin-7

1

7

High-throughput

0.437

High

516289

CGB3
Choriogonadotropin subunit beta 3

1

0

High-throughput

0.426

High

552915

PIP
Prolactin-inducible protein

1

0

High-throughput

0.426

High

654474

CDD
Cytidine deaminase

1

0

High-throughput

0.426

High

505485

ARMS2
Age-related maculopathy susceptibility protein 2

1

1

Small-scale

0.417

High

654543

AP2C
Transcription factor AP-2 gamma

1

10

High-throughput

0.417

High

654572

PHOCN
MOB-like protein phocein

1

1

High-throughput

0.417

High

654550

KLH15
Kelch-like protein 15

1

5

High-throughput

0.407

High

654551

NUDC1
NudC domain-containing protein 1

1

1

High-throughput

0.407

High

654489

IRF9
Interferon regulatory factor 9

2

0

High-throughput

0.328

High

654505

AG10A
Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase

2

0

High-throughput

0.316

High

654509

LCE1F
Late cornified envelope protein 1F

2

0

High-throughput

0.316

High

654514

LCE5A
Late cornified envelope protein 5A

2

0

High-throughput

0.316

High

654532

LMTD2
Lamin tail domain-containing protein 2

2

0

High-throughput

0.316

High

654535

S66A2
Solute carrier family 66 member 2

2

0

High-throughput

0.316

High

654555

UNKL
Putative E3 ubiquitin-protein ligase UNKL

2

0

High-throughput

0.316

High

654566

KAD3
GTP:AMP phosphotransferase AK3, mitochondrial

2

0

High-throughput

0.316

High

654567

CHIC2
Cysteine-rich hydrophobic domain-containing protein 2

2

0

High-throughput

0.316

High

654556

M1IP1
Mid1-interacting protein 1

2

0

High-throughput

0.313

High

154939

BHE40
Class E basic helix-loop-helix protein 40

1

0

High-throughput

0.282

High

654473

3MG
DNA-3-methyladenine glycosylase

1

0

High-throughput

0.269

Low

654508

LCE1D
Late cornified envelope protein 1D

1

0

High-throughput

0.251

Low

654539

MCPH1
Microcephalin

1

0

Small-scale

0.251

Low

654512

ARM12
Armadillo repeat-containing protein 12

1

0

Small-scale

0.249

Low

654573

KAD6
Adenylate kinase isoenzyme 6

1

0

High-throughput

0.238

Low

654499

LAGE3
EKC/KEOPS complex subunit LAGE3

1

0

High-throughput

0.232

Low

654558

DBLOH
Diablo IAP-binding mitochondrial protein

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025