HitPredict

Interactor 1: LAMB1 (P07942)
Laminin subunit beta-1 (Laminin B1 chain) (Laminin-1 subunit beta) (Laminin-10 subunit beta) (Laminin-12 subunit beta) (Laminin-2 subunit beta) (Laminin-6 subunit beta) (Laminin-8 subunit beta)
Gene: LAMB1

Interactor 2: FBX6 (Q9NRD1)
F-box only protein 6 (F-box protein that recognizes sugar chains 2) (F-box/G-domain protein 2)
Gene: FBXO6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.84	0.50	0.650

Property	Details
Experiments	30833792, 32409323, 33961781, 22268729, unassigned3799
Identification Methods	affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 1786 Hs			1 293
+	Hs
		462932 LAMB1_HUMAN (1-1786): 0: 1106: 100.00		FBX2_HUMAN (23-259): 3.8e-119: 345: 49.17
+	Hs
		937444 LAMB2_HUMAN (3-1785): 0: 939: 49.78		FBX6_HUMAN (1-293): 1.16e-178: 495: 100.00
+	Hs
		937450 LAMB2_HUMAN (3-1785): 0: 939: 49.78		FBX2_HUMAN (23-259): 3.8e-119: 345: 49.17
+	Hs
		535895 LAMC1_HUMAN (884-1786): 4.08e-58: 224: 17.04		FBX6_HUMAN (1-293): 1.16e-178: 495: 100.00
+	Hs
		1117023 LAMB3_HUMAN (478-769): 2.34e-17: 90.8: 14.15		FBX6_HUMAN (1-293): 1.16e-178: 495: 100.00
+	Hs
		535905 LAMC1_HUMAN (884-1786): 4.08e-58: 224: 17.04		FBX2_HUMAN (23-259): 3.8e-119: 345: 49.17
+	Hs
		183302 LAMA5_HUMAN (216-367): 1.33e-09: 65.7: 16.20		FBX6_HUMAN (1-293): 1.16e-178: 495: 100.00
+	Hs
		1117041 LAMC2_HUMAN (838-1030): 1.39e-09: 65.5: 30.29		FBX6_HUMAN (1-293): 1.16e-178: 495: 100.00
+	Hs
		1163341 LAMA3_HUMAN (529-700): 8.01e-09: 63: 11.43		FBX6_HUMAN (1-293): 1.16e-178: 495: 100.00
+	Hs
		1460861 NOTC3_HUMAN (596-1270): 1.02e-44: 181: 13.30		FBX2_HUMAN (23-259): 3.8e-119: 345: 49.17
+	Hs
		857586 NOTC1_HUMAN (777-1269): 8.92e-32: 138: 15.46		FBX2_HUMAN (23-259): 3.8e-119: 345: 49.17
+	Hs
		1460886 LAMC3_HUMAN (943-1785): 7.87e-31: 135: 15.48		FBX2_HUMAN (23-259): 3.8e-119: 345: 49.17
+	Hs
		1047775 NOTC2_HUMAN (180-567): 1.26e-27: 125: 12.42		FBX2_HUMAN (23-259): 3.8e-119: 345: 49.17
+	Hs
		1117028 LAMB3_HUMAN (478-769): 2.34e-17: 90.8: 14.15		FBX2_HUMAN (23-259): 3.8e-119: 345: 49.17
+	Hs
		673793 LAMA1_HUMAN (1033-1230): 9.02e-10: 66.5: 20.83		FBX2_HUMAN (23-259): 3.8e-119: 345: 49.17
+	Hs
		183311 LAMA5_HUMAN (216-367): 1.33e-09: 65.7: 16.20		FBX2_HUMAN (23-259): 3.8e-119: 345: 49.17
+	Hs
		1117042 LAMC2_HUMAN (838-1030): 1.39e-09: 65.5: 30.29		FBX2_HUMAN (23-259): 3.8e-119: 345: 49.17
+	Hs
		1157283 LAMA4_HUMAN (440-548): 6.45e-09: 63.5: 34.19		FBX2_HUMAN (23-259): 3.8e-119: 345: 49.17
+	Hs
		1163342 LAMA3_HUMAN (529-700): 8.01e-09: 63: 11.43		FBX2_HUMAN (23-259): 3.8e-119: 345: 49.17