HitPredict

Interactor 1: YES (P07947)
Tyrosine-protein kinase Yes (EC 2.7.10.2) (Proto-oncogene c-Yes) (p61-Yes)
Gene: YES1

Interactor 2: RHOV (Q96L33)
Rho-related GTP-binding protein RhoV (CDC42-like GTPase 2) (GTP-binding protein-like 2) (Rho GTPase-like protein ARHV) (Wnt-1 responsive Cdc42 homolog 2) (WRCH-2)
Gene: RHOV

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PK_Tyr_Ser-Thr~Ras
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 543 Hs			1 236
+	Hs
		463136 YES_HUMAN (1-543): 0: 618: 100.00		RHOU_HUMAN (32-236): 2.91e-89: 265: 60.48
+	Hs
		463050 YES_HUMAN (1-543): 0: 618: 100.00		RAC1_HUMAN (32-217): 7.38e-78: 234: 53.23
+	Hs
		440605 FYN_HUMAN (1-543): 0: 584: 72.16		RHOU_HUMAN (32-236): 2.91e-89: 265: 60.48
+	Hs
		462976 YES_HUMAN (1-543): 0: 618: 100.00		RHOQ_HUMAN (23-236): 1.98e-75: 228: 50.00
+	Hs
		463040 YES_HUMAN (1-543): 0: 618: 100.00		RAC3_HUMAN (32-206): 8.74e-75: 226: 56.00
+	Hs
		462971 YES_HUMAN (1-543): 0: 618: 100.00		RAC2_HUMAN (32-216): 1.84e-74: 225: 52.43
+	Hs
		463043 YES_HUMAN (1-543): 0: 618: 100.00		RHOA_HUMAN (33-215): 4.5e-74: 224: 42.62
+	Hs
		463059 YES_HUMAN (1-543): 0: 618: 100.00		RHOG_HUMAN (30-210): 9.78e-73: 221: 49.17
+	Hs
		557206 SRC_HUMAN (1-543): 0: 602: 74.22		RAC1_HUMAN (32-217): 7.38e-78: 234: 53.23
+	Hs
		463041 YES_HUMAN (1-543): 0: 618: 100.00		CDC42_HUMAN (32-207): 2.13e-66: 205: 57.39
+	Hs
		440481 FYN_HUMAN (1-543): 0: 584: 72.16		RAC1_HUMAN (32-217): 7.38e-78: 234: 53.23
+	Hs
		440334 FYN_HUMAN (1-543): 0: 584: 72.16		RAC2_HUMAN (32-216): 1.84e-74: 225: 52.43
+	Hs
		440473 FYN_HUMAN (1-543): 0: 584: 72.16		RHOA_HUMAN (33-215): 4.5e-74: 224: 42.62
+	Hs
		463224 YES_HUMAN (1-543): 0: 618: 100.00		RHOJ_HUMAN (32-214): 8.34e-59: 186: 50.27
+	Hs
		440471 FYN_HUMAN (1-543): 0: 584: 72.16		CDC42_HUMAN (32-207): 2.13e-66: 205: 57.39
+	Hs
		463321 LYN_HUMAN (1-541): 9.2e-180: 517: 53.69		RHOQ_HUMAN (23-236): 1.98e-75: 228: 50.00
+	Hs
		463428 LYN_HUMAN (1-541): 9.2e-180: 517: 53.69		RAC3_HUMAN (32-206): 8.74e-75: 226: 56.00
+	Hs
		463312 LYN_HUMAN (1-541): 9.2e-180: 517: 53.69		RAC2_HUMAN (32-216): 1.84e-74: 225: 52.43
+	Hs
		463434 LYN_HUMAN (1-541): 9.2e-180: 517: 53.69		RHOA_HUMAN (33-215): 4.5e-74: 224: 42.62
+	Hs
		463430 LYN_HUMAN (1-541): 9.2e-180: 517: 53.69		CDC42_HUMAN (32-207): 2.13e-66: 205: 57.39