HitPredict

Interactor 1: SP1 (P08047)
Transcription factor Sp1
Gene: SP1

Interactor 2: BRCA1 (P38398)
Breast cancer type 1 susceptibility protein (EC 2.3.2.27) (RING finger protein 53) (RING-type E3 ubiquitin transferase BRCA1)
Gene: BRCA1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.64 0.60 0.624

The method score is based on:

Property Details
Experiments 17766039, 12706836
Identification Methods affinity chromatography technology, pull down
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000976 - transcription cis-regulatory region binding
GO:0003677 - DNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
and 6 others

more...
Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 785
Hs

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Service provided by Combinatics, Japan

Last updated: 11Aug2025