HitPredict

Interactor 1: RHOC (P08134)
Rho-related GTP-binding protein RhoC (Rho cDNA clone 9) (h9)
Gene: RHOC

Interactor 2: ACTC (P68032)
Actin, alpha cardiac muscle 1 (EC 3.6.4.-) (Alpha-cardiac actin) [Cleaved into: Actin, alpha cardiac muscle 1, intermediate form]
Gene: ACTC1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0007015 - actin filament organization GO:0070062 - extracellular exosome
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 193 Hs			1 377
+	Hs
		961939 RHOA_HUMAN (1-193): 4.28e-81: 240: 91.71		ACTC_HUMAN (1-377): 0: 599: 100.00
+	Hs
		988263 RAC1_HUMAN (1-193): 6.84e-81: 240: 57.22		ACTC_HUMAN (1-377): 0: 599: 100.00
+	Hs
		952722 RAC1_HUMAN (1-193): 6.84e-81: 240: 57.22		ACTB_HUMAN (4-377): 0: 598: 94.12
+	Hs
		961928 RHOA_HUMAN (1-193): 4.28e-81: 240: 91.71		ACTA_HUMAN (1-377): 0: 597: 98.41
+	Hs
		977675 RHOG_HUMAN (1-193): 2.26e-78: 233: 54.92		ACTA_HUMAN (1-377): 0: 597: 98.41
+	Dm
		386973 RAC1_DROME (1-193): 2.07e-78: 233: 54.12		ACT2_DROME (1-377): 0: 596: 94.16
+	Hs
		580960 RAC2_HUMAN (1-193): 2.92e-77: 231: 54.12		ACTB_HUMAN (4-377): 0: 598: 94.12
+	Hs
		977922 RHOB_HUMAN (1-191): 6.1e-74: 222: 84.82		ACTC_HUMAN (1-377): 0: 599: 100.00
+	Hs
		977923 RHOB_HUMAN (1-191): 6.1e-74: 222: 84.82		ACTS_HUMAN (1-377): 0: 599: 98.94