HitPredict

Interactor 1: RHOC (P08134)
Rho-related GTP-binding protein RhoC (Rho cDNA clone 9) (h9)
Gene: RHOC

Interactor 2: RTKN (Q9BST9)
Rhotekin
Gene: RTKN

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	1.00	0.811

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	PH~Ras
Common GO terms	GO:0000281 - mitotic cytokinesis GO:0005525 - GTP binding GO:0005829 - cytosol GO:0007165 - signal transduction
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 193 Hs			1 563
+	Hs
		962429 RHOA_HUMAN (1-193): 4.28e-81: 240: 91.71		RTKN_HUMAN (1-563): 0: 1053: 100.00
+	Hs
		988661 RAC1_HUMAN (1-193): 6.84e-81: 240: 57.22		RTKN_HUMAN (1-563): 0: 1053: 100.00
+	Mm
		1298097 RHOA_MOUSE (1-193): 1.03e-81: 242: 92.23		RTKN_MOUSE (1-563): 0: 1036: 86.70
+	Hs
		978259 RHOB_HUMAN (1-191): 6.1e-74: 222: 84.82		RTKN_HUMAN (1-563): 0: 1053: 100.00
+	Rn
		962877 RHOA_RAT (1-193): 1.03e-81: 242: 92.23		RTKN_RAT (37-563): 0: 959: 87.50
+	Hs
		466350 RHOC_HUMAN (1-193): 7.6e-80: 237: 100.00		RTKN2_HUMAN (37-486): 0: 730: 42.64
+	Hs
		978150 RHOB_HUMAN (1-191): 6.1e-74: 222: 84.82		RTKN2_HUMAN (37-486): 0: 730: 42.64