HitPredict

Interactor 1: UVRY (P0AED5)
Response regulator UvrY
Gene: UVRY

Interactor 2: FIMZ (P0AEL8)
Fimbriae Z protein
Gene: FIMZ

Species: Escherichia coli K-12

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.57	1.00	0.759

Property	Details
Experiments	19402753, 15690043
Identification Methods	tandem affinity purification, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	GerE~GerE, GerE~Response_reg, Response_reg~Response_reg
Common GO terms	GO:0000160 - phosphorelay signal transduction system GO:0003677 - DNA binding GO:0005737 - cytoplasm GO:0006355 - regulation of DNA-templated transcription
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 218 Ec			1 210
+	Ec
		468921 PHOB_ECOLI (3-214): 1.03e-56: 181: 19.38		PHOB_ECOLI (5-209): 4.58e-55: 176: 15.32
+	Ec
		468178 UVRY_ECOLI (1-218): 6.14e-60: 188: 100.00		UVRY_ECOLI (4-209): 2.7e-49: 161: 25.96
+	Ss
		937544 P72948_SYNY3 (1-211): 1.9e-56: 181: 18.88		P73864_SYNY3 (2-210): 8.06e-50: 163: 23.29
+	Mx
		1091499 Q1D4T4_MYXXD (3-212): 1.67e-54: 175: 18.78		Q1D4T4_MYXXD (2-209): 3.22e-51: 166: 16.59
+	Ec
		465608 PHOB_ECOLI (3-214): 1.03e-56: 181: 19.38		OMPR_ECOLI (2-210): 2.49e-48: 159: 13.42
+	Bs
		533402 DEGU_BACSU (2-211): 2.3e-52: 170: 25.89		DEGU_BACSU (1-210): 1.44e-51: 167: 22.57
+	Mx
		1091446 Q1D1K9_MYXXD (3-214): 1.32e-56: 180: 20.44		Q1D8M8_MYXXD (6-209): 2.86e-46: 154: 20.46
+	Ec
		935858 BAER_ECOLI (3-209): 2.47e-52: 170: 17.57		BAER_ECOLI (2-209): 7.42e-50: 163: 18.22
+	Ec
		465604 OMPR_ECOLI (3-216): 3.72e-53: 172: 16.24		OMPR_ECOLI (2-210): 2.49e-48: 159: 13.42
+	Ec
		940185 HPRR_ECOLI (2-213): 6.28e-53: 171: 15.25		HPRR_ECOLI (4-209): 9.5e-48: 157: 16.90
+	Ec
		439403 CREB_ECOLI (3-210): 5.05e-51: 166: 17.94		CREB_ECOLI (1-209): 1.14e-48: 160: 18.14
+	Ec
		483559 RCSB_ECOLI (2-213): 2.95e-55: 177: 26.05		RCSB_ECOLI (1-203): 1.03e-44: 149: 27.18
+	Ec
		852329 QSEB_ECOLI (2-214): 9.69e-53: 170: 16.00		QSEB_ECOLI (4-209): 1.8e-46: 154: 17.27
+	Ec
		467567 HPRR_ECOLI (2-213): 6.28e-53: 171: 15.25		CUSR_ECOLI (4-210): 1.52e-45: 152: 16.22
+	Ec
		621089 PHOP_ECOLI (2-211): 8.4e-52: 168: 18.02		PHOP_ECOLI (4-210): 5.43e-47: 155: 17.65
+	Bs
		536034 CMPA_BACSU (1-210): 5.84e-51: 166: 24.77		CMPA_BACSU (5-210): 2.71e-47: 156: 25.47
+	Ec
		467563 CUSR_ECOLI (2-209): 1.44e-50: 165: 15.84		CUSR_ECOLI (4-210): 1.52e-45: 152: 16.22