Protein: BUB1
Checkpoint serine/threonine-protein kinase BUB1 (EC 2.7.11.1)

Gene: BUB1
Organism: Saccharomyces cerevisiae S288C
Interactions: 41
UniProt ID: P41695

Gene Ontology (top 5):
GO:0000776 - kinetochore
GO:0000779 - condensed chromosome, centromeric region
GO:0000940 - outer kinetochore
GO:0004672 - protein kinase activity
GO:0004674 - protein serine/threonine kinase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

643042

BUB3
Cell cycle arrest protein BUB3

16

13

Small-scale

0.986

High

783843

BUB1
Checkpoint serine/threonine-protein kinase BUB1

2

17

Small-scale

0.848

High

640849

CDC20
APC/C activator protein CDC20

2

17

Small-scale

0.768

High

778458

MAD1
Spindle assembly checkpoint component MAD1

3

15

Small-scale

0.674

High

775743

DSN1
Kinetochore-associated protein DSN1

4

0

Small-scale

0.649

High

339688

CDK1
Cyclin-dependent kinase 1

1

14

Small-scale

0.647

High

783853

MPS1
Serine/threonine-protein kinase MPS1

1

19

Small-scale

0.647

High

783846

MAD3
Spindle assembly checkpoint component MAD3

1

10

Small-scale

0.618

High

783849

MLC1
Myosin light chain 1

1

13

High-throughput

0.595

High

778482

MAD2
Mitotic spindle checkpoint component MAD2

2

8

Small-scale

0.595

High

731484

YRA2
RNA annealing protein YRA2

1

0

High-throughput

0.589

High

366448

HSP82
ATP-dependent molecular chaperone HSP82

1

20

High-throughput

0.575

High

628172

SIS1
Protein SIS1

1

8

High-throughput

0.575

High

783848

SKP1
Suppressor of kinetochore protein 1

1

2

Small-scale

0.561

High

585326

MYO2
Myosin-2

1

7

High-throughput

0.515

High

783847

UBP15
Ubiquitin carboxyl-terminal hydrolase 15

1

7

High-throughput

0.515

High

356534

H4
Histone H4

1

4

Small-scale

0.501

High

411023

PDC1
Pyruvate decarboxylase isozyme 1

1

1

High-throughput

0.500

High

556111

VATB
V-type proton ATPase subunit B

1

4

High-throughput

0.500

High

560696

BIP
Endoplasmic reticulum chaperone BiP

1

15

High-throughput

0.500

High

756086

ARO9
Aromatic amino acid aminotransferase 2

1

3

High-throughput

0.500

High

602999

BAS1
Myb-like DNA-binding protein BAS1

1

7

High-throughput

0.481

High

746171

STU1
Protein STU1

1

1

High-throughput

0.481

High

783845

ATG18
Autophagy-related protein 18

1

3

Small-scale

0.479

High

764076

RV167
Reduced viability upon starvation protein 167

1

8

High-throughput

0.470

High

783850

SP105
Spindle pole body component SPC105

1

0

Small-scale

0.458

High

783855

SGO1
Shugoshin

1

0

High-throughput

0.458

High

783854

UBC7
Ubiquitin-conjugating enzyme E2 7

1

3

High-throughput

0.457

High

342734

ENO1
Enolase 1

1

5

High-throughput

0.457

High

521006

G6PI
Glucose-6-phosphate isomerase

1

1

High-throughput

0.457

High

491528

HSP71
Heat shock protein SSA1

1

18

High-throughput

0.445

High

494214

HSP72
Heat shock protein SSA2

1

18

High-throughput

0.445

High

511673

SSB1
Ribosome-associated molecular chaperone SSB1

1

20

High-throughput

0.445

High

766058

HSP7E
Heat shock protein SSC3, mitochondrial

1

18

High-throughput

0.445

High

783844

RGD2
Rho-GTPase-activating protein RGD2

1

5

High-throughput

0.439

High

743566

HMT1
Protein arginine N-methyltransferase 1

1

0

High-throughput

0.438

High

783851

DAM1
DASH complex subunit DAM1

1

2

Small-scale

0.437

High

783856

VPS5
Vacuolar protein sorting-associated protein 5

1

0

Small-scale

0.282

High

783852

IST1
Vacuolar protein sorting-associated protein IST1

1

0

High-throughput

0.279

Low

534521

HAP4
Transcriptional activator HAP4

1

0

High-throughput

0.251

Low


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Last updated: 15 Jul 2024