Interactor 1: HS90B (P08238)
Heat shock protein HSP 90-beta (HSP 90) (Heat shock 84 kDa) (HSP 84) (HSP84) (Heat shock protein family C member 3)
Gene: HSP90AB1

Interactor 2: ILK (Q13418)
Scaffold protein ILK (ILK-1) (ILK-2) (Inactive integrin-linked kinase) (p59ILK)
Gene: ILK

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.62 1.00 0.789

The method score is based on:

Property Details
Experiments 32707033, 22939624
Identification Methods affinity chromatography technology, pull down, luminescence based mammalian interactome mapping
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains HSP90~PK_Tyr_Ser-Thr
Common GO terms GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005829 - cytosol
and 3 others

more...

Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 724
Hs

1 452
+ Hs
+ Mm
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+ Hs
+ Hs
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+ Zm
+ At
+ Hs
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Last updated: 11Aug2025