Protein: HS90A
Heat shock protein HSP 90-alpha (EC 3.6.4.10) (Heat shock 86 kDa) (HSP 86) (HSP86) (Tumor-specific transplantation 86 kDa antigen) (TSTA)

Gene: HS90A, Hsp90aa1
Organism: Mus musculus
Interactions: 65
UniProt ID: P07901

Gene Ontology (top 5):
GO:0001764 - neuron migration
GO:0002134 - UTP binding
GO:0002135 - CTP binding
GO:0002218 - activation of innate immune response
GO:0002230 - positive regulation of defense response to virus by host

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

462146

CHRD1
Cysteine and histidine-rich domain-containing protein 1

3

19

Small-scale

0.861

High

462100

AKT1
RAC-alpha serine/threonine-protein kinase

2

20

Small-scale

0.776

High

462115

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

2

17

Small-scale

0.754

High

462149

ITBP2
Integrin beta-1-binding protein 2

2

20

Small-scale

0.751

High

462097

CDK4
Cyclin-dependent kinase 4

1

20

Small-scale

0.647

High

462098

FKBP4
Peptidyl-prolyl cis-trans isomerase FKBP4

1

20

High-throughput

0.621

High

266953

ULK1
Serine/threonine-protein kinase ULK1

1

20

Small-scale

0.618

High

462093

HS90A
Heat shock protein HSP 90-alpha

1

18

Small-scale

0.618

High

462095

BRAF
Serine/threonine-protein kinase B-raf

1

20

High-throughput

0.618

High

462096

KPCD
Protein kinase C delta type

1

20

Small-scale

0.618

High

462099

AHR
Aryl hydrocarbon receptor

1

18

Small-scale

0.618

High

462108

MK01
Mitogen-activated protein kinase 1

1

19

Small-scale

0.618

High

462116

PPP5
Serine/threonine-protein phosphatase 5

1

12

High-throughput

0.618

High

462118

SIM1
Single-minded homolog 1

1

17

Small-scale

0.618

High

462119

CDC37
Hsp90 co-chaperone Cdc37

1

14

Small-scale

0.618

High

462120

HIF1A
Hypoxia-inducible factor 1-alpha

1

17

Small-scale

0.618

High

462122

MK03
Mitogen-activated protein kinase 3

1

19

Small-scale

0.618

High

237346

ILK
Scaffold protein ILK

1

14

Small-scale

0.575

High

462121

M3K7
Mitogen-activated protein kinase kinase kinase 7

1

14

Small-scale

0.575

High

462144

CDK9
Cyclin-dependent kinase 9

1

20

Small-scale

0.575

High

462143

EED
Polycomb protein EED

2

16

Small-scale

0.571

High

462138

TTC23
Tetratricopeptide repeat protein 23

1

1

High-throughput

0.553

High

462105

NPHP4
Nephrocystin-4

1

4

High-throughput

0.536

High

462140

AHI1
Jouberin

1

18

High-throughput

0.536

High

462147

TSC1
Hamartin

1

14

High-throughput

0.536

High

462148

NPHP1
Nephrocystin-1

1

2

High-throughput

0.536

High

462130

EPOP
Elongin BC and Polycomb repressive complex 2-associated protein

1

0

Small-scale

0.513

High

108395

G3X9H5
Huntingtin

1

4

High-throughput

0.479

High

147691

PTEN
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

1

6

High-throughput

0.479

High

462109

IMB1
Importin subunit beta-1

1

8

Small-scale

0.479

High

462110

TRAF6
TNF receptor-associated factor 6

1

15

Small-scale

0.479

High

462112

IRF3
Interferon regulatory factor 3

1

7

Small-scale

0.479

High

462113

STING
Stimulator of interferon genes protein

1

1

High-throughput

0.479

High

462114

UBP48
Ubiquitin carboxyl-terminal hydrolase 48

1

4

High-throughput

0.479

High

462123

NUP62
Nuclear pore glycoprotein p62

1

4

Small-scale

0.479

High

462124

TFE3
Transcription factor E3

1

11

High-throughput

0.479

High

462126

TEDC2
Tubulin epsilon and delta complex protein 2

1

1

High-throughput

0.479

High

462127

NEB2
Neurabin-2

1

7

High-throughput

0.479

High

462128

SPOP
Speckle-type POZ protein

1

10

High-throughput

0.479

High

462129

TRPV1
Transient receptor potential cation channel subfamily V member 1

1

1

High-throughput

0.479

High

462131

FACD2
Fanconi anemia group D2 protein homolog

1

5

High-throughput

0.479

High

462132

WDTC1
WD and tetratricopeptide repeats protein 1

1

20

High-throughput

0.479

High

462134

NOD1
Nucleotide-binding oligomerization domain-containing protein 1

1

12

Small-scale

0.479

High

462135

IQCB1
IQ calmodulin-binding motif-containing protein 1

1

3

High-throughput

0.479

High

462136

A16L1
Autophagy-related protein 16-1

1

15

High-throughput

0.479

High

462145

FBX32
F-box only protein 32

1

2

High-throughput

0.479

High

462094

K2C8
Keratin, type II cytoskeletal 8

1

0

Small-scale

0.458

High

462117

NPT2A
Sodium-dependent phosphate transport protein 2A

1

2

Small-scale

0.457

High

59792

ANR16
Ankyrin repeat domain-containing protein 16

1

17

Small-scale

0.445

High

205709

RB33B
Ras-related protein Rab-33B

1

7

High-throughput

0.445

High

462101

RAB21
Ras-related protein Rab-21

1

8

High-throughput

0.445

High

462102

RAB17
Ras-related protein Rab-17

1

11

High-throughput

0.445

High

462103

GDIA
Rab GDP dissociation inhibitor alpha

1

4

Small-scale

0.445

High

462104

CAV3
Caveolin-3

1

3

High-throughput

0.445

High

462106

RAB1A
Ras-related protein Rab-1A

1

5

High-throughput

0.445

High

462107

RAB3A
Ras-related protein Rab-3A

1

7

High-throughput

0.445

High

462125

Q6AXH7
Histone-lysine N-methyltransferase EZH2

1

10

High-throughput

0.445

High

462137

FTM
Protein fantom

1

13

High-throughput

0.445

High

462139

AGO2
Protein argonaute-2

1

20

Small-scale

0.445

High

462142

RAB4B
Ras-related protein Rab-4B

1

7

High-throughput

0.445

High

462111

STRA8
Stimulated by retinoic acid gene 8 protein

1

0

Small-scale

0.438

High

398024

CFAD
Complement factor D

1

5

High-throughput

0.437

High

462133

BACD1
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1

1

10

High-throughput

0.437

High

462141

FNDC5
Fibronectin type III domain-containing protein 5

1

2

High-throughput

0.437

High


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Last updated: 11Aug2025