HitPredict

Interactor 1: HS90B (P08238)
Heat shock protein HSP 90-beta (HSP 90) (Heat shock 84 kDa) (HSP 84) (HSP84) (Heat shock protein family C member 3)
Gene: HSP90AB1

Interactor 2: SPAG5 (Q96R06)
Sperm-associated antigen 5 (Astrin) (Deepest) (Mitotic spindle-associated protein p126) (MAP126)
Gene: SPAG5

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	40437099
Identification Methods	cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 724 Hs			1 1193
+	Hs
		468128 HS90B_HUMAN (1-724): 0: 1083: 100.00		MYH9_HUMAN (208-1187): 1.01e-40: 166: 10.74
+	Hs
		461208 HS90A_HUMAN (1-724): 0: 1069: 85.25		MYH9_HUMAN (208-1187): 1.01e-40: 166: 10.74
+	Hs
		461087 HS90A_HUMAN (1-724): 0: 1069: 85.25		MYH7_HUMAN (238-962): 3.69e-28: 125: 11.39
+	Hs
		468132 HS90B_HUMAN (1-724): 0: 1083: 100.00		MYH11_HUMAN (149-755): 1.27e-20: 101: 10.15
+	Hs
		468308 HS90B_HUMAN (1-724): 0: 1083: 100.00		CGNL1_HUMAN (628-1192): 8.81e-20: 98.1: 12.57
+	Hs
		468338 HS90B_HUMAN (1-724): 0: 1083: 100.00		ROCK1_HUMAN (546-1186): 1.45e-17: 90.8: 14.97
+	Hs
		461407 HS90A_HUMAN (1-724): 0: 1069: 85.25		CGNL1_HUMAN (628-1192): 8.81e-20: 98.1: 12.57
+	Hs
		156860 HS90B_HUMAN (1-724): 0: 1083: 100.00		CTRO_HUMAN (423-721): 3.13e-10: 66.9: 9.67
+	Hs
		156854 HS90A_HUMAN (1-724): 0: 1069: 85.25		CTRO_HUMAN (423-721): 3.13e-10: 66.9: 9.67
+	Sc
		392299 HSP82_YEAST (12-724): 0: 925: 61.26		USO1_YEAST (150-724): 3.32e-15: 83.4: 9.54
+	Hs
		156908 ENPL_HUMAN (3-693): 0: 914: 46.44		CTRO_HUMAN (423-721): 3.13e-10: 66.9: 9.67