HitPredict

Interactor 1: H2A1 (P0C0S8)
Histone H2A type 1 (H2A.1) (Histone H2A/ptl)
Gene: H2AC11

Interactor 2: SSRP1 (Q08945)
FACT complex subunit SSRP1 (Chromatin-specific transcription elongation factor 80 kDa subunit) (Facilitates chromatin transcription complex 80 kDa subunit) (FACT 80 kDa subunit) (FACTp80) (Facilitates chromatin transcription complex subunit SSRP1) (Recombination signal sequence recognition protein 1) (Structure-specific recognition protein 1) (hSSRP1) (T160)
Gene: SSRP1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.70	1.00	0.839

Property	Details
Experiments	33961781, 34349018, 24463511
Identification Methods	affinity chromatography technology, cross-linking study, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Histone~Rtt106, Histone_H2A_C~Rtt106
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 130 Hs			1 709
+	Hs
		996711 H2A2A_HUMAN (1-130): 6.74e-68: 202: 98.46		SSRP1_HUMAN (1-709): 0: 805: 100.00
+	Hs
		996730 H2A3_HUMAN (1-130): 9.27e-68: 202: 97.69		SSRP1_HUMAN (1-709): 0: 805: 100.00
+	Hs
		391670 H2A1B_HUMAN (1-130): 1.13e-67: 201: 98.46		SSRP1_HUMAN (1-709): 0: 805: 100.00
+	Hs
		996856 H2A1J_HUMAN (1-128): 2.78e-67: 201: 99.22		SSRP1_HUMAN (1-709): 0: 805: 100.00
+	Hs
		996754 H2A2B_HUMAN (1-130): 2.11e-66: 198: 94.62		SSRP1_HUMAN (1-709): 0: 805: 100.00
+	Hs
		996693 H2A2C_HUMAN (1-130): 3.65e-65: 195: 96.92		SSRP1_HUMAN (1-709): 0: 805: 100.00
+	Hs
		996868 H2AJ_HUMAN (1-126): 5.48e-65: 195: 96.03		SSRP1_HUMAN (1-709): 0: 805: 100.00
+	Hs
		555429 H2AX_HUMAN (1-129): 8.34e-64: 192: 91.47		SSRP1_HUMAN (1-709): 0: 805: 100.00
+	Hs
		1151386 H2A2A_HUMAN (1-130): 6.74e-68: 202: 98.46		HM20A_HUMAN (460-709): 1.81e-42: 159: 17.20
+	Hs
		470568 H2A1_HUMAN (1-130): 8.4e-68: 202: 100.00		HM20A_HUMAN (460-709): 1.81e-42: 159: 17.20
+	Hs
		391917 H2A1B_HUMAN (1-130): 1.13e-67: 201: 98.46		HM20A_HUMAN (460-709): 1.81e-42: 159: 17.20
+	Hs
		1087107 H2A2C_HUMAN (1-130): 3.65e-65: 195: 96.92		HM20A_HUMAN (460-709): 1.81e-42: 159: 17.20
+	Hs
		555655 H2AX_HUMAN (1-129): 8.34e-64: 192: 91.47		HM20A_HUMAN (460-709): 1.81e-42: 159: 17.20
+	Hs
		594829 H2A1D_HUMAN (1-130): 9.47e-68: 202: 99.23		SOX2_HUMAN (516-636): 8.67e-30: 122: 22.31
+	Sc
		392263 H2A2_YEAST (16-128): 2.5e-59: 180: 80.53		NHP6A_YEAST (530-619): 6.02e-28: 109: 35.56
+	Sc
		392264 H2A2_YEAST (16-128): 2.5e-59: 180: 80.53		NHP6B_YEAST (520-619): 7.39e-28: 109: 34.00
+	Hs
		643357 H2A2A_HUMAN (1-130): 6.74e-68: 202: 98.46		HMGB2_HUMAN (540-698): 5.17e-15: 76.3: 23.53
+	Hs
		449745 H2A2A_HUMAN (1-130): 6.74e-68: 202: 98.46		HMGB1_HUMAN (543-634): 1e-14: 75.5: 34.04
+	Hs
		643395 H2A1J_HUMAN (1-128): 2.78e-67: 201: 99.22		HMGB2_HUMAN (540-698): 5.17e-15: 76.3: 23.53
+	Hs
		449762 H2A2B_HUMAN (1-130): 2.11e-66: 198: 94.62		HMGB1_HUMAN (543-634): 1e-14: 75.5: 34.04