Interactor 1: FBSP1 (P0C2W1)
F-box/SPRY domain-containing protein 1 (F-box only protein 45) (hFbxo45)
Gene: FBXO45

Interactor 2: FBXW7 (Q969H0)
F-box/WD repeat-containing protein 7 (Archipelago homolog) (hAgo) (F-box and WD-40 domain-containing protein 7) (F-box protein FBX30) (SEL-10) (hCdc4)
Gene: FBXW7

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.82 1.00 0.908

The method score is based on:

Property Details
Experiments 31285543, 25720964, 28514442, 33961781
Identification Methods affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains F-box-like~F-box-like
Common GO terms GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0006974 - DNA damage response
GO:0016567 - protein ubiquitination
GO:0019005 - SCF ubiquitin ligase complex
and 2 others

more...

Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 286
Hs

1 707
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024