HitPredict

Interactor 1: NFIC (P08651)
Nuclear factor 1 C-type (NF1-C) (Nuclear factor 1/C) (CCAAT-box-binding transcription factor) (CTF) (Nuclear factor I/C) (NF-I/C) (NFI-C) (TGGCA-binding protein)
Gene: NFIC

Interactor 2: MED17 (Q9NVC6)
Mediator of RNA polymerase II transcription subunit 17 (Activator-recruited cofactor 77 kDa component) (ARC77) (Cofactor required for Sp1 transcriptional activation subunit 6) (CRSP complex subunit 6) (Mediator complex subunit 17) (Thyroid hormone receptor-associated protein complex 80 kDa component) (Trap80) (Transcriptional coactivator CRSP77) (Vitamin D3 receptor-interacting protein complex 80 kDa component) (DRIP80)
Gene: MED17

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	39617063
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006357 - regulation of transcription by RNA polymerase II GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 508 Hs			1 651
+	Hs
		1133694 NFIX_HUMAN (2-507): 2.18e-156: 456: 56.73		MED17_HUMAN (1-651): 0: 1032: 100.00
+	Hs
		1088053 NFIA_HUMAN (2-508): 1.69e-133: 398: 59.20		MED17_HUMAN (1-651): 0: 1032: 100.00
+	Hs
		143290 NFIB_HUMAN (1-423): 2.41e-128: 381: 63.47		MED17_HUMAN (1-651): 0: 1032: 100.00
+	Hs
		787899 SRBP1_HUMAN (293-455): 4.45e-21: 99.2: 15.06		MED17_HUMAN (1-651): 0: 1032: 100.00
+	Hs
		667476 RPB1_HUMAN (374-496): 2.4e-09: 62.2: 20.33		MED17_HUMAN (1-651): 0: 1032: 100.00