HitPredict

Interactor 1: UBC (P0CG48)
Polyubiquitin-C [Cleaved into: Ubiquitin]
Gene: UBC

Interactor 2: CDC42 (P60953)
Cell division control protein 42 homolog (EC 3.6.5.2) (G25K GTP-binding protein)
Gene: CDC42

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.63	0.60	0.619

Property	Details
Experiments	31478661, 20936779
Identification Methods	pull down, two hybrid, two hybrid pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005789 - endoplasmic reticulum membrane GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0070062 - extracellular exosome
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 685 Hs			1 191
+	Hs
		475593 UBC_HUMAN (1-685): 0: 846: 100.00		RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31
+	Hs
		475625 UBC_HUMAN (1-685): 0: 846: 100.00		RHOG_HUMAN (1-191): 7.59e-82: 242: 60.73
+	Hs
		475558 UBC_HUMAN (1-685): 0: 846: 100.00		RHOA_HUMAN (5-191): 3.88e-81: 240: 53.48
+	At
		656930 UBQ3_ARATH (457-685): 3.23e-85: 272: 95.63		RAD2A_ARATH (4-185): 1.42e-76: 229: 24.04
+	Hs
		923947 RS27A_HUMAN (609-684): 7.23e-41: 148: 100.00		RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31
+	Hs
		900357 RS27A_HUMAN (609-684): 7.23e-41: 148: 100.00		RHOA_HUMAN (5-191): 3.88e-81: 240: 53.48
+	Rn
		1144214 UBC_RAT (1-108): 1.27e-29: 127: 90.74		RAC1_RAT (1-191): 1.75e-84: 249: 70.31
+	Mm
		476750 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		RAC1_MOUSE (1-191): 1.75e-84: 249: 70.31
+	Rn
		1144234 UBC_RAT (1-108): 1.27e-29: 127: 90.74		CDC42_RAT (1-191): 4.96e-82: 243: 100.00
+	Rn
		1104200 UBC_RAT (1-108): 1.27e-29: 127: 90.74		Q32PX6_RAT (1-191): 7.59e-82: 242: 60.73
+	Hs
		475188 UBB_HUMAN (1-77): 7.83e-26: 108: 98.70		RHOJ_HUMAN (2-188): 2.67e-85: 252: 64.17
+	Hs
		474987 UBB_HUMAN (1-77): 7.83e-26: 108: 98.70		RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31
+	Hs
		475074 UBB_HUMAN (1-77): 7.83e-26: 108: 98.70		RHOU_HUMAN (4-186): 1.03e-72: 221: 58.82