HitPredict

Interactor 1: UBC (P0CG48)
Polyubiquitin-C [Cleaved into: Ubiquitin]
Gene: UBC

Interactor 2: MIRO2 (Q8IXI1)
Mitochondrial Rho GTPase 2 (MIRO-2) (hMiro-2) (EC 3.6.5.-) (Ras homolog gene family member T2)
Gene: RHOT2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005741 - mitochondrial outer membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 685 Hs			1 618
+	Hs
		475548 UBC_HUMAN (1-685): 0: 846: 100.00		CDC42_HUMAN (3-172): 5.67e-77: 244: 25.54
+	Hs
		475625 UBC_HUMAN (1-685): 0: 846: 100.00		RHOG_HUMAN (3-170): 1.68e-74: 238: 27.47
+	Hs
		475593 UBC_HUMAN (1-685): 0: 846: 100.00		RAC1_HUMAN (3-181): 3.15e-74: 237: 26.43
+	Hs
		475558 UBC_HUMAN (1-685): 0: 846: 100.00		RHOA_HUMAN (6-168): 1.74e-11: 65.5: 28.25
+	Hs
		476409 UBC_HUMAN (1-685): 0: 846: 100.00		RHOF_HUMAN (2-167): 3.37e-11: 65.1: 26.67
+	Rn
		1144227 UBC_RAT (1-108): 1.27e-29: 127: 90.74		MIRO2_RAT (1-618): 0: 749: 84.24
+	Sc
		350834 UBI4P_YEAST (381-685): 5e-122: 370: 95.74		YPT1_YEAST (416-588): 9.61e-32: 123: 18.54
+	At
		656930 UBQ3_ARATH (457-685): 3.23e-85: 272: 95.63		RAD2A_ARATH (416-593): 8.17e-44: 157: 18.82
+	Hs
		923947 RS27A_HUMAN (609-684): 7.23e-41: 148: 100.00		RAC1_HUMAN (3-181): 3.15e-74: 237: 26.43
+	Rn
		1144234 UBC_RAT (1-108): 1.27e-29: 127: 90.74		CDC42_RAT (3-172): 5.67e-77: 244: 25.54
+	Rn
		1104200 UBC_RAT (1-108): 1.27e-29: 127: 90.74		Q32PX6_RAT (3-170): 1.68e-74: 238: 27.47
+	Rn
		1144214 UBC_RAT (1-108): 1.27e-29: 127: 90.74		RAC1_RAT (3-181): 3.15e-74: 237: 26.43
+	Mm
		476750 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		RAC1_MOUSE (3-181): 3.15e-74: 237: 26.43
+	Hs
		474987 UBB_HUMAN (1-77): 7.83e-26: 108: 98.70		RAC1_HUMAN (3-181): 3.15e-74: 237: 26.43
+	Rn
		102473 UBC_RAT (1-108): 1.27e-29: 127: 90.74		G3V6H0_RAT (416-578): 1.42e-38: 142: 19.05
+	Rn
		936845 UBC_RAT (1-108): 1.27e-29: 127: 90.74		RAB8B_RAT (411-571): 1.26e-27: 112: 16.27
+	Hs
		900357 RS27A_HUMAN (609-684): 7.23e-41: 148: 100.00		RHOA_HUMAN (6-168): 1.74e-11: 65.5: 28.25
+	Hs
		397887 ISG15_HUMAN (228-380): 1.72e-28: 113: 32.69		RB11A_HUMAN (416-572): 8.23e-22: 96.2: 20.37
+	Rn
		916116 UBC_RAT (1-108): 1.27e-29: 127: 90.74		RHOB_RAT (6-168): 4.57e-13: 70.1: 29.38
+	Hs
		474983 UBB_HUMAN (1-77): 7.83e-26: 108: 98.70		RHOB_HUMAN (6-168): 4.57e-13: 70.1: 29.38