HitPredict

Interactor 1: UBC (P0CG48)
Polyubiquitin-C [Cleaved into: Ubiquitin]
Gene: UBC

Interactor 2: UBP7 (Q93009)
Ubiquitin carboxyl-terminal hydrolase 7 (EC 3.4.19.12) (Deubiquitinating enzyme 7) (Herpesvirus-associated ubiquitin-specific protease) (Ubiquitin thioesterase 7) (Ubiquitin-specific-processing protease 7)
Gene: USP7

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.97	1.00	0.985

Property	Details
Experiments	29576527, 30651545, 33141564, 34642328, 36114200, 38803224, 14506283, 27256865, 29056420, 29045385, 27501351, 29249604, 34129829, 17651432, 20622874, 22195557, 23287719
Identification Methods	pull down, affinity chromatography technology, enzymatic study, x-ray crystallography, unspecified method
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	UCH~ubiquitin
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0016567 - protein ubiquitination
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 685 Hs			1 1102
+	At
		1091741 UBQ3_ARATH (457-685): 3.23e-85: 272: 95.63		UBP13_ARATH (14-1102): 0: 1003: 35.63
+	Hs
		476213 UBC_HUMAN (1-685): 0: 846: 100.00		UBP47_HUMAN (208-737): 3.48e-107: 368: 26.62
+	Hs
		476452 UBC_HUMAN (1-685): 0: 846: 100.00		UBP40_HUMAN (173-765): 1.3e-101: 350: 21.12
+	Hs
		475995 UBC_HUMAN (1-685): 0: 846: 100.00		UBP48_HUMAN (206-572): 1.45e-102: 349: 26.90
+	Hs
		475952 UBC_HUMAN (1-685): 0: 846: 100.00		UBP34_HUMAN (125-644): 3.97e-99: 348: 18.81
+	Hs
		476579 UBC_HUMAN (1-685): 0: 846: 100.00		UBP22_HUMAN (45-521): 2.51e-107: 347: 16.43
+	Hs
		476146 UBC_HUMAN (1-685): 0: 846: 100.00		USP9X_HUMAN (173-554): 7.42e-97: 341: 23.08
+	Hs
		131635 UBC_HUMAN (1-685): 0: 846: 100.00		USP9Y_HUMAN (186-564): 2.64e-96: 340: 22.64
+	Hs
		475932 UBC_HUMAN (1-685): 0: 846: 100.00		U17L2_HUMAN (158-684): 1.09e-103: 338: 19.05
+	Hs
		476580 UBC_HUMAN (1-685): 0: 846: 100.00		UBP24_HUMAN (200-587): 2.93e-95: 337: 24.41
+	Hs
		476400 UBC_HUMAN (1-685): 0: 846: 100.00		UBP42_HUMAN (162-683): 1.67e-95: 334: 18.44
+	Hs
		476493 UBC_HUMAN (1-685): 0: 846: 100.00		UBP36_HUMAN (165-651): 1.45e-94: 328: 18.13
+	Hs
		475566 UBC_HUMAN (1-685): 0: 846: 100.00		UBP46_HUMAN (204-522): 1.27e-91: 299: 25.50
+	Hs
		64200 UBC_HUMAN (1-685): 0: 846: 100.00		UBP27_HUMAN (187-521): 3.14e-90: 298: 20.05
+	Hs
		259261 UBC_HUMAN (1-685): 0: 846: 100.00		UBP12_HUMAN (189-522): 1.4e-89: 294: 25.55
+	Sc
		477365 UBI4P_YEAST (381-685): 5e-122: 370: 95.74		UBP15_YEAST (58-1102): 0: 719: 27.74
+	At
		1210479 UBQ10_ARATH (305-685): 2.63e-153: 453: 95.80		UBP15_ARATH (125-696): 1.39e-103: 349: 17.65
+	Sc
		477366 UBI4P_YEAST (381-685): 5e-122: 370: 95.74		UBP8_YEAST (131-519): 2.12e-90: 300: 21.98
+	Mm
		476669 UBB_MOUSE (457-685): 2.3e-86: 275: 99.56		UBP48_MOUSE (206-572): 1.33e-102: 349: 27.45
+	At
		1092065 UBQ3_ARATH (457-685): 3.23e-85: 272: 95.63		UBP15_ARATH (125-696): 1.39e-103: 349: 17.65