HitPredict

Interactor 1: UBC (P0CG48)
Polyubiquitin-C [Cleaved into: Ubiquitin]
Gene: UBC

Interactor 2: EP15R (Q9UBC2)
Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R)
Gene: EPS15L1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.602

Property	Details
Experiments	28190767, 38803224
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 685 Hs			1 864
+	Hs
		475452 UBC_HUMAN (1-685): 0: 846: 100.00		EPS15_HUMAN (1-862): 3.59e-115: 374: 42.20
+	Hs
		475816 UBC_HUMAN (1-685): 0: 846: 100.00		ITSN1_HUMAN (1-522): 2.39e-32: 138: 13.31
+	Hs
		476483 UBC_HUMAN (1-685): 0: 846: 100.00		ITSN2_HUMAN (2-531): 1.52e-24: 112: 11.86
+	Rn
		88639 UBC_RAT (1-108): 1.27e-29: 127: 90.74		D3ZJR1_RAT (1-862): 1.65e-125: 402: 91.67
+	Mm
		476822 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		EP15R_MOUSE (1-862): 1.06e-124: 399: 92.11
+	Sc
		477209 UBI4P_YEAST (381-685): 5e-122: 370: 95.74		EDE1_YEAST (9-832): 2.37e-28: 125: 10.51
+	Mm
		476700 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		EPS15_MOUSE (1-862): 8.21e-97: 325: 41.30
+	Rn
		1126748 UBC_RAT (1-108): 1.27e-29: 127: 90.74		Q5JC29_RAT (1-782): 2.53e-93: 313: 42.20
+	Sc
		477280 UBI4P_YEAST (381-685): 5e-122: 370: 95.74		END3_YEAST (17-310): 4.94e-09: 61.2: 14.38
+	Mm
		477062 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		ITSN1_MOUSE (2-556): 1.43e-30: 132: 13.55
+	Mm
		70590 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		B2RR82_MOUSE (2-537): 7.73e-26: 117: 12.48
+	Rn
		1144238 UBC_RAT (1-108): 1.27e-29: 127: 90.74		Q8R3Z7_RAT (203-369): 5.35e-22: 103: 26.63