HitPredict

Interactor 1: UBIQP (P0CG69)
Polyubiquitin [Cleaved into: Ubiquitin]
Gene: Ubi-p63E

Interactor 2: LUBEL (Q8IPJ3)
E3 ubiquitin-protein ligase lubel (EC 2.3.2.31) (Linear Ubiquitin E3 ligase)
Gene: LUBEL

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.52	0.80	0.648

Property	Details
Experiments	27702987
Identification Methods	affinity chromatography technology, enzymatic study
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	E3_UbLigase_RBR~ubiquitin, IBR~ubiquitin
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 763 Dm			1 2892
+	Dm
		1214032 Q9W418_DROME (1-230): 9.66e-92: 298: 99.13		LUBEL_DROME (1-2892): 0: 1205: 100.00
+	Mm
		476959 UBC_MOUSE (77-762): 0: 854: 99.85		RNF31_MOUSE (2258-2889): 2.63e-132: 447: 28.28
+	Hs
		476630 UBC_HUMAN (153-762): 0: 766: 99.84		ARI1_HUMAN (2419-2885): 2.33e-133: 433: 18.33
+	Hs
		476187 UBC_HUMAN (153-762): 0: 766: 99.84		RNF31_HUMAN (2256-2889): 1.39e-124: 424: 28.04
+	Hs
		312458 UBC_HUMAN (153-762): 0: 766: 99.84		ARI2_HUMAN (2370-2864): 2.52e-124: 404: 14.80
+	Rn
		1144287 UBC_RAT (1-713): 0: 874: 99.02		PRKN_RAT (2340-2728): 5.15e-70: 246: 15.68
+	Mm
		476729 UBC_MOUSE (77-762): 0: 854: 99.85		RN216_MOUSE (1981-2741): 9.82e-66: 244: 15.64
+	Hs
		475976 UBC_HUMAN (153-762): 0: 766: 99.84		R144B_HUMAN (2496-2754): 5.25e-77: 260: 19.40
+	Hs
		476496 UBC_HUMAN (153-762): 0: 766: 99.84		AKIB1_HUMAN (2408-2881): 1.8e-68: 256: 14.41
+	Hs
		475494 UBC_HUMAN (153-762): 0: 766: 99.84		R144A_HUMAN (2510-2754): 1.5e-72: 247: 20.47
+	Hs
		475939 UBC_HUMAN (153-762): 0: 766: 99.84		RN19B_HUMAN (2509-2765): 2.33e-65: 240: 21.85
+	Hs
		226335 UBC_HUMAN (153-762): 0: 766: 99.84		PRKN_HUMAN (2376-2726): 1.96e-67: 238: 15.59
+	Sc
		477225 UBI4P_YEAST (457-762): 3.6e-121: 370: 95.75		HEL1_YEAST (2418-2837): 2.1e-88: 302: 14.79
+	Hs
		312457 UBB_HUMAN (1-77): 8.33e-27: 111: 98.70		ARI2_HUMAN (2370-2864): 2.52e-124: 404: 14.80
+	Hs
		475094 UBB_HUMAN (1-77): 8.33e-27: 111: 98.70		CUL9_HUMAN (2385-2869): 4.96e-89: 328: 15.74
+	At
		1092233 UBQ3_ARATH (533-762): 2.94e-94: 297: 95.65		Q9M1E9_ARATH (2507-2742): 1.94e-32: 134: 20.32
+	Hs
		227107 RS27A_HUMAN (685-760): 1.11e-40: 148: 100.00		PRKN_HUMAN (2376-2726): 1.96e-67: 238: 15.59
+	Hs
		475069 UBB_HUMAN (1-77): 8.33e-27: 111: 98.70		RN19B_HUMAN (2509-2765): 2.33e-65: 240: 21.85
+	Hs
		171468 UBD_HUMAN (155-304): 6.65e-28: 112: 32.05		PRKN_HUMAN (2376-2726): 1.96e-67: 238: 15.59
+	Hs
		226334 UBB_HUMAN (1-77): 8.33e-27: 111: 98.70		PRKN_HUMAN (2376-2726): 1.96e-67: 238: 15.59