HitPredict

Interactor 1: RL40A (P0CH08)
Ubiquitin-ribosomal protein eL40A fusion protein [Cleaved into: Ubiquitin; Large ribosomal subunit protein eL40A (60S ribosomal protein L40-A) (CEP52)]
Gene: RPL40A

Interactor 2: UFD4 (P33202)
Ubiquitin fusion degradation protein 4 (UB fusion protein 4) (EC 2.3.2.-) (HECT-type E3 ubiquitin transferase UFD4) (EC 2.3.2.26)
Gene: UFD4

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	16554755
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	HECT~ubiquitin
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 128 Sc			1 1483
+	Sc
		477197 UBI4P_YEAST (1-76): 6.46e-42: 143: 100.00		UFD4_YEAST (1-1483): 0: 1249: 100.00
+	Hs
		125347 RS27A_HUMAN (1-88): 1.83e-37: 126: 84.09		WWP2_HUMAN (610-1480): 0: 722: 16.39
+	Hs
		924156 RS27A_HUMAN (1-88): 1.83e-37: 126: 84.09		WWP1_HUMAN (640-1480): 0: 660: 16.18
+	Sc
		477647 RL40A_YEAST (1-128): 8.56e-54: 166: 100.00		TOM1_YEAST (595-1483): 1.37e-167: 562: 16.87
+	Sp
		145418 RL402_SCHPO (1-128): 4.52e-53: 164: 96.88		PUB3_SCHPO (842-1480): 3.5e-180: 558: 17.44
+	Hs
		924414 RL40_HUMAN (1-128): 3.98e-55: 170: 89.84		SMUF2_HUMAN (905-1479): 2.06e-176: 547: 17.30
+	Sc
		477424 UBI4P_YEAST (1-76): 6.46e-42: 143: 100.00		TOM1_YEAST (595-1483): 1.37e-167: 562: 16.87
+	Sc
		477293 UBI4P_YEAST (1-76): 6.46e-42: 143: 100.00		RSP5_YEAST (774-1480): 1.01e-176: 550: 15.57
+	At
		1091762 UBQ3_ARATH (1-77): 4.92e-34: 121: 96.10		UPL2_ARATH (768-1483): 7.17e-158: 534: 18.80
+	At
		1091951 UBQ3_ARATH (1-77): 4.92e-34: 121: 96.10		IMPA1_ARATH (83-591): 8.8e-175: 534: 12.86
+	Hs
		924302 RL40_HUMAN (1-128): 3.98e-55: 170: 89.84		HERC3_HUMAN (826-1481): 1.62e-149: 485: 19.36
+	At
		97780 UBQ3_ARATH (1-77): 4.92e-34: 121: 96.10		IMPA2_ARATH (83-591): 2.3e-173: 531: 13.44
+	At
		285378 UBQ3_ARATH (1-77): 4.92e-34: 121: 96.10		IMPA4_ARATH (77-593): 6.57e-155: 482: 15.12
+	Dm
		89880 RL40_DROME (1-128): 2.38e-55: 170: 91.41		D5SHR3_DROME (1031-1480): 1.05e-137: 432: 21.29
+	At
		1091758 UBQ3_ARATH (1-77): 4.92e-34: 121: 96.10		UPL1_ARATH (1025-1483): 8.97e-112: 394: 24.68
+	Hs
		924434 RL40_HUMAN (1-128): 3.98e-55: 170: 89.84		HECD1_HUMAN (1277-1475): 3.61e-27: 123: 35.44
+	Hs
		924336 RL40_HUMAN (1-128): 3.98e-55: 170: 89.84		HUWE1_HUMAN (1191-1483): 1.44e-20: 101: 31.51
+	Sp
		143368 UBI4P_SCHPO (1-77): 3.56e-42: 144: 98.70		PTR1_SCHPO (1195-1480): 4.03e-24: 113: 29.11
+	Mm
		924239 RS27A_MOUSE (1-88): 2.05e-37: 125: 84.09		HUWE1_MOUSE (1191-1483): 1.76e-20: 101: 31.51
+	Hs
		983151 Q5U5U6_HUMAN (1-76): 2.09e-32: 115: 96.05		UBE3A_HUMAN (1204-1482): 2.39e-21: 103: 29.17