HitPredict

Interactor 1: HSP77 (P0CS90)
Import motor subunit, mitochondrial (EC 3.6.4.10) (Endonuclease SceI 75 kDa subunit) (Endo.SceI 75 kDa subunit) (mtHSP70)
Gene: SSC1

Interactor 2: AFG3 (P39925)
Mitochondrial inner membrane m-AAA protease component YTA10 (EC 3.4.24.-) (EC 3.6.-.-) (ATPase family gene 3 protein) (Tat-binding homolog 10)
Gene: AFG3

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	25792736, 11805837
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005739 - mitochondrion GO:0005743 - mitochondrial inner membrane GO:0016887 - ATP hydrolysis activity GO:0030150 - protein import into mitochondrial matrix
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 654 Sc			1 761
+	Sc
		478249 HSP77_YEAST (1-654): 0: 896: 100.00		YTA12_YEAST (22-747): 3.09e-167: 504: 52.52
+	Hs
		871843 HSP72_HUMAN (28-654): 0: 850: 47.20		AFG32_HUMAN (1-756): 0: 549: 45.06
+	Hs
		751898 GRP75_HUMAN (16-654): 0: 788: 64.90		AFG32_HUMAN (1-756): 0: 549: 45.06
+	At
		1107020 HS704_ARATH (25-649): 0: 870: 47.74		FTSH1_ARATH (42-729): 1.55e-145: 445: 37.59
+	Sc
		478031 HSP77_YEAST (1-654): 0: 896: 100.00		YME1_YEAST (64-755): 1.19e-131: 410: 27.79
+	Sc
		477952 HSP77_YEAST (1-654): 0: 896: 100.00		CDC48_YEAST (87-555): 5.82e-101: 331: 24.24