Protein: RU1A
U1 small nuclear ribonucleoprotein A (U1 snRNP A) (U1-A) (U1A) (Mutant U1 die protein 1)

Gene: RU1A, MUD1
Organism: Saccharomyces cerevisiae S288C
Interactions: 84
UniProt ID: P32605

Gene Ontology (top 5):
GO:0000243 - commitment complex
GO:0000395 - mRNA 5'-splice site recognition
GO:0000398 - mRNA splicing, via spliceosome
GO:0005634 - nucleus
GO:0005681 - spliceosomal complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

743543

NAM8
Protein NAM8

8

1

Small-scale

0.968

High

743544

RU17
U1 small nuclear ribonucleoprotein 70 kDa homolog

8

1

Small-scale

0.968

High

743561

NCBP2
Nuclear cap-binding protein subunit 2

7

1

Small-scale

0.960

High

743553

SNU56
56 kDa U1 small nuclear ribonucleoprotein component

8

0

Small-scale

0.919

High

743516

NCBP1
Nuclear cap-binding protein complex subunit 1

6

0

Small-scale

0.894

High

743547

NOP3
Serine/arginine

4

1

Small-scale

0.878

High

743523

PRP39
Pre-mRNA-processing factor 39

8

1

Small-scale

0.751

High

743552

PRP42
U1 small nuclear ribonucleoprotein component PRP42

7

2

Small-scale

0.747

High

743510

RU1A
U1 small nuclear ribonucleoprotein A

2

0

Small-scale

0.736

High

743512

PRP40
Pre-mRNA-processing protein PRP40

9

0

Small-scale

0.722

High

743534

SNU71
U1 small nuclear ribonucleoprotein component SNU71

10

0

Small-scale

0.722

High

625077

PRP9
Pre-mRNA-splicing factor PRP9

2

0

High-throughput

0.716

High

743562

RU2A
U2 small nuclear ribonucleoprotein A'

2

0

Small-scale

0.716

High

743564

BBP
Branchpoint-bridging protein

2

0

Small-scale

0.716

High

743556

RU1C
U1 small nuclear ribonucleoprotein C

7

0

Small-scale

0.715

High

743526

RSMB
Small nuclear ribonucleoprotein-associated protein B

6

0

Small-scale

0.702

High

743527

RUXG
Small nuclear ribonucleoprotein G

6

0

Small-scale

0.699

High

743548

SMD1
Small nuclear ribonucleoprotein Sm D1

5

0

Small-scale

0.684

High

743560

LUC7
Protein LUC7

5

0

Small-scale

0.684

High

743529

SMD3
Small nuclear ribonucleoprotein Sm D3

4

0

Small-scale

0.664

High

743559

SMD2
Small nuclear ribonucleoprotein Sm D2

4

0

Small-scale

0.664

High

721788

XPO1
Exportin-1

1

0

High-throughput

0.656

High

743542

RUXF
Small nuclear ribonucleoprotein F

3

0

Small-scale

0.632

High

743566

RUXE
Small nuclear ribonucleoprotein E

3

0

Small-scale

0.632

High

743563

YRA1
RNA annealing protein YRA1

1

1

High-throughput

0.618

High

743569

HSH49
Protein HSH49

1

1

High-throughput

0.618

High

743519

MUD2
Splicing factor MUD2

3

0

Small-scale

0.613

High

403419

PABP
Polyadenylate-binding protein, cytoplasmic and nuclear

1

0

High-throughput

0.586

High

743515

LHP1
La protein homolog

1

0

High-throughput

0.586

High

743532

SF3B1
U2 snRNP component HSH155

1

0

High-throughput

0.586

High

743549

CUS1
Cold sensitive U2 snRNA suppressor 1

1

0

High-throughput

0.586

High

743555

RSE1
Pre-mRNA-splicing factor RSE1

1

0

High-throughput

0.586

High

743545

PTA1
Pre-tRNA-processing protein PTA1

2

0

High-throughput

0.585

High

594268

RPB3
DNA-directed RNA polymerase II subunit RPB3

2

0

Small-scale

0.559

High

739116

PRP19
Pre-mRNA-processing factor 19

2

0

Small-scale

0.547

High

743565

PUF2
mRNA-binding protein PUF2

1

0

High-throughput

0.517

High

687036

PPZ1
Serine/threonine-protein phosphatase PP-Z1

1

0

High-throughput

0.486

High

743558

FKBP4
FK506-binding protein 4

1

0

High-throughput

0.486

High

743521

RRP3
ATP-dependent rRNA helicase RRP3

1

2

High-throughput

0.481

High

444465

DED1
ATP-dependent RNA helicase DED1

1

1

High-throughput

0.479

High

453919

IF4E
Eukaryotic translation initiation factor 4E

1

0

High-throughput

0.458

High

624990

PRP6
Pre-mRNA-splicing factor 6

1

0

High-throughput

0.458

High

645340

XRN1
5'-3' exoribonuclease 1

1

0

High-throughput

0.458

High

666423

DBP2
ATP-dependent RNA helicase DBP2

1

0

High-throughput

0.458

High

678639

PAT1
Deadenylation-dependent mRNA-decapping factor PAT1

1

0

High-throughput

0.458

High

700079

PRP45
Pre-mRNA-processing protein 45

1

0

High-throughput

0.458

High

706556

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

742999

SWI3
SWI/SNF complex subunit SWI3

1

0

High-throughput

0.458

High

743511

BRR2
Pre-mRNA-splicing helicase BRR2

1

0

High-throughput

0.458

High

743514

PRP8
Pre-mRNA-splicing factor 8

1

0

High-throughput

0.458

High

743517

SN114
Pre-mRNA-splicing factor SNU114

1

0

High-throughput

0.458

High

743518

SHE2
SWI5-dependent HO expression protein 2

1

0

Small-scale

0.458

High

743522

LSM12
Protein LSM12

1

0

High-throughput

0.458

High

743528

ACA2
ATF/CREB activator 2

1

0

High-throughput

0.458

High

743530

SET2
Histone-lysine N-methyltransferase, H3 lysine-36 specific

1

0

High-throughput

0.458

High

743531

PRP31
Pre-mRNA-processing factor 31

1

0

High-throughput

0.458

High

743536

PBP1
PAB1-binding protein 1

1

0

High-throughput

0.458

High

743539

SWT21
Protein SWT21

1

0

High-throughput

0.458

High

743540

NAF1
H/ACA ribonucleoprotein complex non-core subunit NAF1

1

0

High-throughput

0.458

High

743541

APJ1
J domain-containing protein APJ1

1

0

High-throughput

0.458

High

743546

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

1

0

High-throughput

0.458

High

743550

IMA1
Importin subunit alpha

1

0

High-throughput

0.458

High

743557

IMB1
Importin subunit beta-1

1

0

High-throughput

0.458

High

743567

SNU66
66 kDa U4/U6.U5 small nuclear ribonucleoprotein component

1

0

Small-scale

0.458

High

743568

BRR1
Pre-mRNA-splicing factor BRR1

1

0

High-throughput

0.458

High

743524

IF4F1
Eukaryotic initiation factor 4F subunit p150

1

1

High-throughput

0.437

High

743525

IF4F2
Eukaryotic initiation factor 4F subunit p130

1

1

High-throughput

0.437

High

544224

SSB1
Ribosome-associated molecular chaperone SSB1

1

0

High-throughput

0.426

High

741217

HSP7F
Heat shock protein homolog SSE1

1

0

High-throughput

0.426

High

149203

FOB1
DNA replication fork-blocking protein FOB1

1

0

High-throughput

0.265

Low

743538

JJJ1
J protein JJJ1

1

0

High-throughput

0.265

Low

585236

FBRL
rRNA 2'-O-methyltransferase fibrillarin

1

0

High-throughput

0.249

Low

671315

CANB
Calcineurin subunit B

1

0

High-throughput

0.249

Low

721589

RENT1
ATP-dependent helicase NAM7

1

0

High-throughput

0.249

Low

735453

AAR2
A1 cistron-splicing factor AAR2

1

0

High-throughput

0.249

Low

738086

MYO4
Myosin-4

1

0

Small-scale

0.249

Low

743513

CBF5
H/ACA ribonucleoprotein complex subunit CBF5

1

0

High-throughput

0.249

Low

743520

SHE3
SWI5-dependent HO expression protein 3

1

0

Small-scale

0.249

Low

743533

IMDH3
Inosine-5'-monophosphate dehydrogenase 3

1

0

High-throughput

0.249

Low

743535

EIF2A
Eukaryotic translation initiation factor 2A

1

0

High-throughput

0.249

Low

743537

BRE5
UBP3-associated protein BRE5

1

0

High-throughput

0.249

Low

743551

EBS1
Nonsense-mediated mRNA decay factor EBS1

1

0

High-throughput

0.249

Low

743554

DHR1
Probable ATP-dependent RNA helicase DHR1

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025