Interactor 1: HSP77 (P0CS90)
Import motor subunit, mitochondrial (EC 3.6.4.10) (Endonuclease SceI 75 kDa subunit) (Endo.SceI 75 kDa subunit) (mtHSP70)
Gene: SSC1

Interactor 2: TIM44 (Q01852)
Mitochondrial import inner membrane translocase subunit TIM44 (Inner membrane import site protein 45) (ISP45) (Membrane import machinery protein MIM44) (Mitochondrial protein import protein 1)
Gene: TIM44

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.97 0.60 0.767

The method score is based on:

Property Details
Experiments 23864706, 7809127, 9171336, 12677068, 10913171, 10352014, 9155010, 25792736, 15719019, 24829379, 20007714, 19036727, 11273703, 12032075, 10367886, 8530381, 11564892, 11733493, 17881357, 37968396 and 3 others

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Identification Methods affinity chromatography technology, pull down, two hybrid, biochemical, miniaturized immunoprecipitation, tandem affinity purification
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0001405 - PAM complex, Tim23 associated import motor
GO:0005524 - ATP binding
GO:0005739 - mitochondrion
GO:0005743 - mitochondrial inner membrane
GO:0005744 - TIM23 mitochondrial import inner membrane translocase complex
and 2 others

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Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 654
Sc

1 431
+ Sc
+ Hs
+ Sc

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Last updated: 15 Jul 2024