Protein: FGF1
Fibroblast growth factor 1 (FGF-1) (Acidic fibroblast growth factor) (aFGF) (Endothelial cell growth factor) (ECGF) (Heparin-binding growth factor 1) (HBGF-1)

Gene: FGF1
Organism: Homo sapiens
Interactions: 45
UniProt ID: P05230

Gene Ontology (top 5):
GO:0001525 - angiogenesis
GO:0001759 - organ induction
GO:0005104 - fibroblast growth factor receptor binding
GO:0005178 - integrin binding
GO:0005576 - extracellular region

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

426932

FGFR1
Fibroblast growth factor receptor 1

23

20

Small-scale

0.989

High

426937

FGFR2
Fibroblast growth factor receptor 2

13

20

Small-scale

0.981

High

426939

FGFR3
Fibroblast growth factor receptor 3

7

20

Small-scale

0.963

High

426938

FGFR4
Fibroblast growth factor receptor 4

6

20

Small-scale

0.944

High

426950

PGBM
Basement membrane-specific heparan sulfate proteoglycan core protein

2

7

Small-scale

0.789

High

426931

FGF1
Fibroblast growth factor 1

2

3

Small-scale

0.755

High

426963

S10AD
Protein S100-A13

2

1

Small-scale

0.755

High

426941

SDC4
Syndecan-4

3

8

High-throughput

0.667

High

426943

GPC1
Glypican-1 [Cleaved into: Secreted glypican-1]

3

8

High-throughput

0.667

High

426951

TGBR3
Transforming growth factor beta receptor type 3

3

1

High-throughput

0.667

High

426960

PLCD3
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3

1

0

High-throughput

0.656

High

426949

CLD10
Claudin-10

3

0

High-throughput

0.638

High

426964

HM20A
High mobility group protein 20A

3

0

High-throughput

0.638

High

426945

GPC3
Glypican-3

2

8

High-throughput

0.628

High

426961

Q8NI16
Fibroblast growth factor receptor 3

1

20

Small-scale

0.618

High

426936

SYT1
Synaptotagmin-1

1

0

Small-scale

0.614

High

246393

KDM1A
Lysine-specific histone demethylase 1A

2

1

High-throughput

0.611

High

426966

RCOR3
REST corepressor 3

2

2

High-throughput

0.611

High

426968

RCOR1
REST corepressor 1

2

2

High-throughput

0.611

High

426956

EGFLA
Pikachurin

3

6

High-throughput

0.609

High

426946

PFD3
Prefoldin subunit 3

2

0

High-throughput

0.580

High

426944

HSPA9
Stress-70 protein, mitochondrial

1

4

Small-scale

0.573

High

426947

CSK2B
Casein kinase II subunit beta

1

2

Small-scale

0.561

High

426942

SDC2
Syndecan-2

2

9

High-throughput

0.558

High

426934

SDC1
Syndecan-1

2

9

High-throughput

0.549

High

426955

NEDD8
Ubiquitin-like protein NEDD8

1

0

Small-scale

0.537

High

426948

CSK21
Casein kinase II subunit alpha

1

4

Small-scale

0.536

High

283642

GPC4
Glypican-4

1

8

High-throughput

0.536

High

426959

KLHL7
Kelch-like protein 7

1

1

High-throughput

0.536

High

426967

GT2D1
General transcription factor II-I repeat domain-containing protein 1

1

1

High-throughput

0.536

High

426969

FARP1
FERM, ARHGEF and pleckstrin domain-containing protein 1

1

3

High-throughput

0.536

High

426965

EXOS5
Exosome complex component RRP46

1

0

High-throughput

0.513

High

215967

FIBP
Acidic fibroblast growth factor intracellular-binding protein

1

0

Small-scale

0.504

High

426935

CSK22
Casein kinase II subunit alpha'

1

4

Small-scale

0.501

High

426940

PTX3
Pentraxin-related protein PTX3

1

10

Small-scale

0.501

High

426952

FGFP1
Fibroblast growth factor-binding protein 1

1

5

Small-scale

0.501

High

426957

RL7L
Ribosomal protein uL30-like

1

1

High-throughput

0.489

High

426954

PLEC
Plectin

1

2

High-throughput

0.479

High

426971

GPC6
Glypican-6 [Cleaved into: Secreted glypican-6]

1

8

High-throughput

0.479

High

426933

CD44
CD44 antigen

1

2

High-throughput

0.445

High

426962

SRPK1
SRSF protein kinase 1

1

5

High-throughput

0.445

High

426953

GSE1
Genetic suppressor element 1

3

0

High-throughput

0.347

High

426958

CEFIP
Cardiac-enriched FHL2-interacting protein

1

0

High-throughput

0.279

Low

426970

TRPV2
Transient receptor potential cation channel subfamily V member 2

1

0

Small-scale

0.238

Low


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Last updated: 11Aug2025