Interactor 1: GRPE (P09372)
Protein GrpE (HSP-70 cofactor) (HSP24) (Heat shock protein B25.3)
Gene: GRPE
Interactor 2: DNAK (P0A6Y8)
Chaperone protein DnaK (HSP70) (Heat shock 70 kDa protein) (Heat shock protein 70)
Gene: DNAK
Species: Escherichia coli K-12
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.80 | 1.00 | 0.896 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 16606699, 28524877, 9103205, 15690043 |
| Identification Methods | affinity chromatography technology, cross-linking study, x-ray crystallography, surface plasmon resonance, pull down, tandem affinity purification |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | GrpE~HSP70 |
| Common GO terms | GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0009408 - response to heat GO:0032991 - protein-containing complex GO:0043335 - protein unfolding and 3 others more... |
| Homologous interactions | 5 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
