Protein: GRPE
GrpE protein homolog, mitochondrial

Gene: GRPE, MGE1
Organism: Saccharomyces cerevisiae S288C
Interactions: 69
UniProt ID: P38523

Gene Ontology (top 5):
GO:0000774 - adenyl-nucleotide exchange factor activity
GO:0001405 - PAM complex, Tim23 associated import motor
GO:0005739 - mitochondrion
GO:0005743 - mitochondrial inner membrane
GO:0005744 - TIM23 mitochondrial import inner membrane translocase complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

510450

HSP77
Import motor subunit, mitochondrial

23

5

Small-scale

0.988

High

800364

HSP7Q
Iron-sulfur cluster biogenesis chaperone, mitochondrial

3

6

Small-scale

0.861

High

800338

GRPE
GrpE protein homolog, mitochondrial

3

5

Small-scale

0.845

High

800344

HSP7E
Heat shock protein SSC3, mitochondrial

2

5

Small-scale

0.754

High

800356

TIM44
Mitochondrial import inner membrane translocase subunit TIM44

5

0

Small-scale

0.684

High

399829

COX4
Cytochrome c oxidase subunit 4, mitochondrial

3

0

Small-scale

0.619

High

523799

HSP71
Heat shock protein SSA1

1

0

Small-scale

0.614

High

676884

MXR2
Peptide methionine sulfoxide reductase 2

2

0

Small-scale

0.603

High

626713

HSP60
Heat shock protein 60, mitochondrial

2

1

High-throughput

0.595

High

752203

HSP78
Heat shock protein 78, mitochondrial

2

1

High-throughput

0.584

High

746990

PREP
Presequence protease, mitochondrial

2

3

High-throughput

0.571

High

746828

TIM23
Mitochondrial import inner membrane translocase subunit TIM23

2

0

Small-scale

0.560

High

800353

BTN2
Protein BTN2

2

0

High-throughput

0.551

High

734550

MSS51
Protein MSS51, mitochondrial

2

0

High-throughput

0.547

High

800345

SSB2
Ribosome-associated molecular chaperone SSB2

1

0

High-throughput

0.546

High

763429

MDJ1
DnaJ homolog 1, mitochondrial

1

4

Small-scale

0.515

High

800341

MLH1
DNA mismatch repair protein MLH1

1

0

High-throughput

0.513

High

800346

NTA1
Protein N-terminal amidase

1

0

High-throughput

0.513

High

800340

CH10
10 kDa heat shock protein, mitochondrial

1

3

High-throughput

0.501

High

746345

RAD54
DNA repair and recombination protein RAD54

1

1

High-throughput

0.489

High

738633

EI2BB
Translation initiation factor eIF2B subunit beta

1

0

High-throughput

0.486

High

800348

FMP32
Protein FMP32, mitochondrial

1

2

High-throughput

0.481

High

594938

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, mitochondrial

1

1

High-throughput

0.479

High

604944

MDHM
Malate dehydrogenase, mitochondrial

1

1

High-throughput

0.479

High

673632

BOS1
Protein transport protein BOS1

1

0

High-throughput

0.460

High

800365

YET3
Endoplasmic reticulum transmembrane protein 3

1

0

High-throughput

0.460

High

452658

ADH3
Alcohol dehydrogenase 3, mitochondrial

1

0

High-throughput

0.458

High

456392

ILVB
Acetolactate synthase catalytic subunit, mitochondrial

1

0

High-throughput

0.458

High

654600

AIM17
Probable oxidoreductase AIM17

1

0

High-throughput

0.458

High

673332

TRX3
Thioredoxin-3, mitochondrial

1

0

High-throughput

0.458

High

673499

STDH
Catabolic L-serine/threonine dehydratase [Includes: L-serine dehydratase

1

0

High-throughput

0.458

High

701517

IDH2
Isocitrate dehydrogenase [NAD] subunit 2, mitochondrial

1

0

High-throughput

0.458

High

800343

ILV3
Dihydroxy-acid dehydratase, mitochondrial

1

0

High-throughput

0.458

High

800351

ALDH4
Potassium-activated aldehyde dehydrogenase, mitochondrial

1

0

High-throughput

0.458

High

800362

COX20
Cytochrome c oxidase assembly protein COX20, mitochondrial

1

0

High-throughput

0.458

High

800368

HSP42
Heat shock protein 42

1

0

High-throughput

0.458

High

800359

STE20
Serine/threonine-protein kinase STE20

1

1

High-throughput

0.457

High

800350

YFI6
Uncharacterized protein YFR016C

1

1

High-throughput

0.437

High

394509

EF1A
Elongation factor 1-alpha

1

0

High-throughput

0.426

High

453571

PYR1
Multifunctional protein URA2

1

0

High-throughput

0.426

High

800366

SCC1
Sister chromatid cohesion protein 1

1

0

Small-scale

0.426

High

486454

TBA3
Tubulin alpha-3 chain

1

1

High-throughput

0.407

High

592221

VATB
V-type proton ATPase subunit B

1

1

High-throughput

0.407

High

800357

ULP1
Ubiquitin-like-specific protease 1

2

0

High-throughput

0.306

High

678320

RSC6
Chromatin structure-remodeling complex protein RSC6

1

0

High-throughput

0.282

High

672306

RV161
Reduced viability upon starvation protein 161

1

0

High-throughput

0.279

Low

684068

MGMT
Methylated-DNA--protein-cysteine methyltransferase

1

0

High-throughput

0.279

Low

709367

HRR25
Casein kinase I homolog HRR25

1

0

High-throughput

0.279

Low

758500

SLD2
DNA replication regulator SLD2

1

0

High-throughput

0.279

Low

800349

YPI1
Type 1 phosphatases regulator YPI1

1

0

High-throughput

0.279

Low

800363

HEL2
E3 ubiquitin-protein ligase HEL2

1

0

High-throughput

0.279

Low

750235

PRP40
Pre-mRNA-processing protein PRP40

1

0

High-throughput

0.261

Low

735617

SMY1
Kinesin-related protein SMY1

1

0

High-throughput

0.251

Low

755057

TIP20
Protein transport protein TIP20

1

0

High-throughput

0.251

Low

800339

LNP
Endoplasmic reticulum junction formation protein lunapark

1

0

High-throughput

0.251

Low

800342

END3
Actin cytoskeleton-regulatory complex protein END3

1

0

High-throughput

0.251

Low

800352

MPS3
Spindle pole body assembly component MPS3

1

0

High-throughput

0.251

Low

800354

AF9
Protein AF-9 homolog

1

0

High-throughput

0.251

Low

800355

MDM1
Structural protein MDM1

1

0

High-throughput

0.251

Low

800358

CENPP
Inner kinetochore subunit CTF19

1

0

High-throughput

0.251

Low

800360

VPS20
Vacuolar protein sorting-associated protein 20

1

0

High-throughput

0.251

Low

800361

SPC24
Kinetochore protein SPC24

1

0

High-throughput

0.251

Low

800367

GIN4
Serine/threonine-protein kinase GIN4

1

0

High-throughput

0.251

Low

531721

RL4A
Large ribosomal subunit protein uL4A

1

0

High-throughput

0.249

Low

706970

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.249

Low

776561

DEF1
RNA polymerase II degradation factor 1

1

0

High-throughput

0.249

Low

631912

SRP54
Signal recognition particle subunit SRP54

1

0

High-throughput

0.232

Low

800347

MPG1
Mannose-1-phosphate guanyltransferase

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025